Article Types

Research

Intensive lipid‐lowering therapy in the 12 months after an acute coronary syndrome in Australia: an observational analysis

The known: People who have experienced an acute coronary syndrome (ACS) are at high risk of further events. High blood cholesterol is an important modifiable factor that increases the risks of both initial and subsequent ACS events. The new: Only 55% of patients treated in Australia for ACS were undergoing intensive lipid‐lowering therapy 6 or 12 months after their hospitalisation. The major predictor of not receiving such therapy at follow‐up was its not being prescribed at hospital discharge. The implications: Improving oral lipid‐lowering therapy for people who have had an ACS should prevent recurrent coronary events.

David Brieger · Mario D'Souza · Karice Hyun · James C Weaver · Leonard Kritharides

Mja2 12035

Pregabalin misuse‐related ambulance attendances in Victoria, 2012–2017: characteristics of patients and attendances

The known: Pregabalin misuse is increasing worldwide, and is associated with acute psychiatric and medical harms, but patterns of pregabalin misuse in Australia have not been reported. The new: The rate of pregabalin‐related ambulance attendances has increased tenfold since 2012, associated with an increase in the national prescription rate. Patients frequently misused pregabalin with other sedatives, particularly benzodiazepines, and almost 40% of misuse‐related events requiring paramedic attendance were suicide attempts. The implications: Caution is required when prescribing pregabalin for patients using other sedatives. Misuse might be reduced by restricting dispensing of the drug.

Rose Crossin · Debbie Scott · Shalini Arunogiri · Karen Smith · Paul M Dietze · Dan I Lubman

Mja2 12036
Cancer Research 24 September 2018 Free

Surveillance improves survival of patients with hepatocellular carcinoma: a prospective population-based study

Survival may be improved by surveillance, as it enables curative therapies to be initiated

Thai P Hong · Paul J Gow · Michael Fink · Anouk Dev · Stuart K Roberts · Amanda Nicoll · John S Lubel · Ian Kronborg · Niranjan Arachchi · Marno Ryan · William W Kemp · Virginia Knight · Vijaya Sundararajan · Paul Desmond · Alexander JV Thompson · Sally J Bell

18 00373

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