Topics
Anatomy and physiology
Disease‐specific survival for people with chronic myeloid leukaemia, South Australia, 1980–2020: a retrospective cohort study
Disease-specific mortality for people with CML has declined substantially with the introduction of tyrosine kinase inhibitors
Kerri Beckmann · Brendon J Kearney · Naranie Shanmuganathan · David Yeung · Tim Hughes
Who gets asthma, and why?
A combine-to-cure approach is essential, simultaneously preventing harmful exposures and directed at the underlying biological mechanisms
Denby J Evans · Peter D Sly · Paul Foster · Chantal Donovan
Technological advances in the search for a CURE for asthma
Combining new technologies with artificial intelligence will enable more accurate disease prediction, precision diagnoses, and personalised treatments
Sara Quon · Timothy M Johanson · Ridhima Wadhwa · Alen Faiz · Anthony Flynn · Gary P Anderson · Amanda J Cox · Nicholas P West · Michael P Menden · Rhys S Allan
The first Australian evidence‐based guidelines on male infertility
These first Australian evidence-based guidelines will serve as a clinical aid to practitioners who provide services to men with infertility and will facilitate evidence-based care for the most common areas of male infertility
Darren J Katz · Liza O’Donnell · Robert I McLachlan · Tim J Moss · Clare V Boothroyd · Veena Jayadev · Sarah R Catford
Sex differences in management and outcomes of people with ST‐elevation myocardial infarction, New South Wales, 2011–2020: a retrospective cohort study
Sex differences are declining but will not be eliminated during the next ten years
Samia Kazi · Simone Marschner · Haeri Min · Desi Quintans · James JH Chong · Ehsan Khan · David B Brieger · Clara K Chow
Lung cancer biobanking in Australia: challenges and future directions
Overview of lung cancer biobanking globally and in Australia, challenges such as difficulty with tissue acquisition, the usefulness of biospecimens in multi-omic analysis, as well as unique challenges faced in Australia
Sarah Yeo · Stephen Q Wong · Farzaneh Atashrazm · Andreas Behren · Anthony T Papenfuss · Natalia Vukelic · Lisa Briggs · Ashleigh R Poh · Daniel Steinfort · Natasha Smallwood · Kate Sutherland · Vivek Naranbhai · Sagun Parakh · Tracy Leong
Severe hypoglycaemia secondary to chronic opioid‐induced hypothalamic–pituitary–adrenal axis suppression: an under‐recognised phenomenon
A 49-year-old woman with type 2 diabetes mellitus was hospitalised with critical hypoglycaemia
Michael Do · Annabelle G Hayes · Malgorzata M Brzozowska
Updating the diagnosis and management of iron deficiency in the era of routine ferritin testing of blood donors by Australian Red Cross Lifeblood
Jason Abbott · Kirsten I Black · Elizabeth Marles
Improving cardiometabolic risk factors in Aboriginal and Torres Strait Islander people in northeast Arnhem Land: single arm trial of a co‐designed dietary and lifestyle program
Culturally acceptable strategies for improving risk factors could reduce cardiometabolic disease in remote Aboriginal and Torres Strait Islander communities
Hasthi UW Dissanayake · George Gurruwiwi · J Dhurrkay · Josh C Tynan · Sabine Braat · Benjamin Harrap · Tim Trudgen · Sarah Hanieh · Bronwyn Clark · Michaela Spencer · Michael Christie · Emma Tonkin · Emily Armstrong · Leonard C Harrison · John M Wentworth · Julie K Brimblecombe · Beverley‐Ann Biggs
Gender affirmation testosterone therapy, Australia, 2021–22: a review of PBS dispensing data
Knowing how many people use testosterone for gender affirmation is important for service provision and quality of care
Brendan J Nolan · Sav Zwickl · Jeffrey D Zajac · Ada S Cheung
Genetic testing in cardiovascular disease
Andrew C Martin · Ari E Horton · Shubha Srinivasan
Paracoccidioidomycosis: an Australian case
A 34-year-old man, born in Brasília, Brazil, who had been living in Australia for three years with no return travel, presented to his dentist with an eight-week history of a painful, progressively enlarging maxillary, gingival ulcerative lesion
Timothy C Badrick · Ella M Meumann · Kathryn Shirley · Peter Simos · Mertya L May · Gary Quagliotto · Evan C Bursle · Nici Leonard · Rodney J McDougall · Jennifer M Robson
Averting infections when implanting cardiac pacemakers and defibrillators
Documenting reasons for implanting CIEDs and detailed discussions with prospective patients about their risks are essential
William F Heddle AM
Which reference equation should we use for interpreting spirometry values for First Nations Australians? A cross‐sectional study
The normal spirometry values of healthy First Nations Australians may be substantially higher than previously reported
Andrew J Collaro · Rachel Foong · Anne B Chang · Julie M Marchant · Tamara L Blake · Johanna F Cole · Glenn Pearson · Rebecca Hii · Henry Brown · Mark D Chatfield · Graham Hall · Margaret S McElrea
Prevalence, pathogenesis and spectrum of neurological symptoms in COVID‐19 and post‐COVID‐19 syndrome
Josef Finsterer · Fulvio A Scorza
The not‐so‐natural herb: a case of exogenous Cushing syndrome
A 44-year-old man presented to the emergency department with one month of worsening breathlessness, orthopnoea, paroxysmal nocturnal dyspnoea, and pitting oedema to the thighs
Yi‐An Pan · David Roberts · Yi‐An Pan · David Roberts
Increased prescribing of psychotropic medication for children and adolescents during the COVID‐19 pandemic: no cause for alarm
Alain Braillon · Wendy A Rogers
Neurotoxic risks from over‐the‐counter vitamin supplements
A 40-year-old man was referred to the neuromuscular clinic with generalised fasciculations
Dhayalen Krishnan · Matthew C Kiernan
Cervical cord infarction mimicking migraine in a patient with vertebral artery dissection
Careful clinical assessment is indicated in migraineurs to differentiate between migraine and more serious neurological pathologies
Alanna Rottler · Yew Li Dang · Wai Foong Hooi · David Burrows · Hong Kuan Kok · Douglas Crompton
Mycobacterium haemophilum in a patient with inflammatory bowel disease
A 38-year-old woman with longstanding Crohn’s disease presented with 7 months of a nonhealing widespread rash
Fleur W Kong · David Wong · Kendall Sharpe · Louis Pool · James Muir
The management of peri‐operative anaemia in patients undergoing major abdominal surgery in Australia and New Zealand: a prospective cohort study
The management of peri-operative anaemia after major abdominal surgery should be standardised to improve patient outcomes
The POSTVenTT Study Collaborative*
Skeletons in the closet: time to give human bones acquired by health practitioners for educational purposes the respect they deserve
To the Editor: The concepts presented by Coman and colleagues1 parallel international trends within anatomical societies, where attitudes on human remains used for educational purposes are under scrutiny.2 Illuminating issues around legacy collections, and pressing for further clarity, transparency and appropriate cultural and ethical solutions, is important for the proper treatment of these precious resources. It is also necessary given recent events that have raised concerns within the public about how human remains and anatomical collections are treated under the guise of education.3 We strongly support the points made by Coman et al around development of repatriation policies for privately held bones, but we respectfully suggest additional considerations. The suggestion “Medical ethicists assert that in the absence of consent, anatomical specimens … should be destroyed”1 is not congruent with current suggestions and practice.4 Anatomical collections that have no provenance or consent are often used as teaching resources and represent the tangible legacies of histories of this field of science. As such, they serve the additional educational purpose of eliciting discussions on contemporary ethical and professional practice.5 There are also benefits associated with using real bones as opposed to three‐dimensional or plastic copies that do not retain the same weight, detail or nuanced anatomical features. Arguments do exist for disposition of unconsented collections, but these should be considered against the educational value these remains deliver and the social, ethical and cultural concerns around their ongoing use. In proposing consultation across various groups to clarify appropriate practice around “managing the legacy of human bone use in education,“1 we suggest it is necessary to include other specific interest groups to ensure community‐appropriate practices are developed. It is essential that community input is acquired, with indigenous representatives contributing knowledge and perspective. In addition, input from organisations that contribute expertise specific to national and international standards and practice are necessary. This should include local organisations, the Australian Institute of Anatomical Sciences and the Australian and New Zealand Association of Clinical Anatomists, and globally, the International Federation of Associations of Anatomists ethics committee. Such broad input is necessary to ensure guidelines are fit for purpose in a global education community.
Jon Cornwall · Sabine Hildebrandt · Thomas Champney
Clinical gene technology in Australia: building on solid foundations
Many technical and regulatory hurdles have been overcome, but the field has a long way to go
Gabrielle O'Sullivan · Joshua G Philips · John EJ Rasko
Pulling the plug on the stem cell hype
Flesh made new: the unnatural history and broken promise of stem cells
Megan Munsie
Should clinicians and the general population be concerned about seasonal affective disorder in Australia?
Seasonal affective disorder, a well documented syndrome in northern latitudes, has limited credence in Australia
Adriana G Nevarez Flores · Emmanuelle CS Bostock · Amanda L Neil