Immune system diseases

We report a case of a kidney transplant recipient who presented with generalised muscle pain, weakness and brown urine discoloration in the setting of acute severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Investigations demonstrated rhabdomyolysis with elevated creatine kinase levels and severe acute kidney injury (AKI). A muscle biopsy was consistent with an immune-mediated necrotising myositis. The patient received intravenous fluids, remdesivir and haemodialysis, with subsequent resolution of muscle injury and recovery of kidney function. This case indicates the potential for severe myositis to develop in patients with SARS-CoV-2 infection with the potential for rhabdomyolysis and AKI to occur.

Navya Kataria, Abel Devadass, Lana Sundac, Laura De Souza, Nabeel Sheikh, Samantha Ng, Scott Campbell, Yishen Wang, Ross S. Francis

Uterus transplantation could be adopted as an assisted reproductive technology for women with uterine factor infertility

Rebecca Deans · Brigitte Gerstl · Antonia W Shand · Sarah Lyons · Aaron Budden · Helen L Barrett · Grant Luxton · Mangalee Fernando · Kenneth Yong · Karen Keung · Kaushalya Arulpragasam · Henry Pleass · King Man Wan · Eva Kehag · Jana‐Emily Pittman · Mianna Lotz · Maria Fenn · Erin Nesbitt‐Hawes · Lily Byun · Katrina Tang · Mats Brannstrom · Jason Abbott

A multisectoral approach and stronger multilevel government coordination are required to address the health impacts associated with proximity to mining and exposure to toxic chemicals

Javier Cortes‐Ramirez · Ruby N Michael · Leisa‐Maree Toms · Melissa Haswell

An 18-year-old Australian, Indigenous woman with no medical history presented with five months of small joint polyarthralgia and Raynaud phenomenon

Michael Taggart · Mina John

A 39-year-old woman underwent bilateral sequential lung transplantation for fibrotic hypersensitivity pneumonitis in May 2022

Alyssa Pradhan · David Pham · Alexander Brennan · Jen Kok · Priya Garg

A 76-year-old female patient was urgently referred to the endocrine clinic for suppressed morning serum cortisol levels

Mike Lin · Lisa Horgan · Albert Hsieh

A 64-year-old man of European descent presented to a tertiary hospital in the Northern Territory with a four-week history of fevers, headaches, coughing and dyspnoea

Sara Davison · Tanmay Kanitkar · Dimitrios Menouhos · Thomas Ewin · Catherine S Marshall · Peter Boan · Sonja Janson

A 72-year-old man with a history of well controlled type 2 diabetes was admitted to a tertiary metropolitan hospital for investigation of fevers, night sweats and unintentional weight loss of 18kg over six months

Vinny Ea · Brigitte Papa · Rimma Goldberg

Novel anti-amyloid therapies have generated hope in Alzheimer disease. Although the therapies are generally well tolerated, there are important side effects that need consideration

Oneil G Bhalala · Jane Thompson · Rosie Watson · Nawaf Yassi

A 77-year-old man with maize starch excipient allergy on peritoneal dialysis presented to the renal clinic with mild right groin pain for a week, blood pressure of 150/79 mmHg, and weight gain of 2 kg due to fluid retention

Lipin Lukose · Shrey Seth · Kamal Sud · Brian Nankivell · Mary Ann Nicdao · Ronald L Castelino

Anti-inflammatory drugs can reduce cardiovascular events, but risks, benefits and mediating mechanisms are still uncertain

Samia Kazi · James J H Chong · Clara K Chow

Multidisciplinary models of care including dietary therapy are needed in Australia

Jessica Fitzpatrick · Sarah L Melton · Rebecca E Burgell

A 61-year-old man of European ancestry presented with five large fungating lesions

Michelle Wu · Nicole Seebacher · Margit Polcz

Helen Y Sun · Yaron Gu · Deshan F Sebaratnam

The long term impact of COVID-19 on neurological diseases remains uncertain and requires ongoing vigilance through longitudinal studies

Robb Wesselingh