Article Types

Medical education

Cluster randomised trials

Cluster randomised trials randomise groups of individuals rather than individuals themselves to interventions. The groups might be communities, schools, workplaces, hospitals, or patients treated by a particular doctor. There are a number of reasons for the use of cluster trials as opposed to individually randomised trials. They may be the only available choice, as when a city is randomised to a mass intervention.

Michael J Campbell

Mja2 13001

Revisiting the antinuclear antibody test with emphasis on a new pattern: anti‐DFS70 antibody

ANA by indirect immunofluorescence remains the method of choice for screening patients suspected of having SARDs. A positive ANA test should be followed by further testing for ENA and dsDNA antibody testing for defining the ANA specificities and disease associations. The presence of anti‐DFS70 antibody in absence of ENA and dsDNA antibodies effectively excludes a diagnosis of SARD.

Pravin Hissaria · Andrew Broadfoot · Karl W Baumgart

Mja2 12103

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