Pharmacology

There was a dramatic increase in intentional exposures to ADHD medications between 2004 and 2014

Rose Cairns PhD, BPharm(Hons) · Benjamin Daniels MA, BSc · Danielle A Wood MB BS, FACEM · Jonathan Brett MB BS(Hons), FRACP, FAChAM

An update on research advances in this field that may help tackle this growing challenge more effectively

Terence WH Chong MB BS, MP, FRANZCP · Samantha M Loi MB BS, FRANZCP, GradCertPOA · Nicola T Lautenschlager MD, FRANZCP · David Ames BA, MD, FRCPsych

Concerns regarding efficacy and safety in real-world populations

Nicole L Pratt PhD · Emmae N Ramsay BSc, GradDipAppStats, MClinEpi · Gillian E Caughey PhD · Sepehr Shakib MB BS, FRACP, PhD · Elizabeth E Roughead BPharm, MAppSc, PhD

Start prepregnancy counselling early and discontinue teratogenic medications

Gene-Siew Ngian MB BS, FRACP, PhD · Andrew M Briggs BSc(PT)Hons, PhD · Ilana N Ackerman PhD, BPhysio(Hons) · Sharon Van Doornum MB BS, MD, FRACP

Ten years of data on eligibility to initiate and continue on bDMARDs remains un-utilised

Ashley M Hopkins BPharm(Hons) · Susanna M Proudman MB BS(Hons), FRACP · Agnes I Vitry PhD, MEcManageHealthSyst, BPharm · Michael J Sorich PhD, GradDipMedStat, BPharm(Hons) · Leslie G Cleland MB BS, MD, FRACP · Michael D Wiese BPharm, MClinPharm, PhD

Early administration of antibiotics and aggressive fluid resuscitation improves outcomes for patients

Anthony R Burrell MB BS, FANZCA, FCICM · Mary-Louise McLaws DipTropPubHlth, MPH, PhD · Mary Fullick RN, BHlthSci(Nurs) · Rosemary B Sullivan RN, BHlthSci(Admin), MBus(HRM) · Doungkamol Sindhusake PhD, MPH, MA

Lack of data on drug safety is concerning

Tilenka Thynne MB BS, FRACP · Genevieve M Gabb MB BS(Hons), FRACP, GradDipClinEpi

Shifting cultural and financial reliance away from pharmaceutical company sponsorship

Jessica Dean BMedSci(Hons) · Erwin Loh MB BS, PhD, FRACMA · Justin J Coleman MB BS, FRACGP, MPH

Encouraging evidence about expanding access to medications and reducing cardiovascular risk among Indigenous Australians

Amal N Trivedi MD, MPH · Allan J Pollack MB BS(Hons), FRACS(Orth), MPH(PP) · Helena C Britt BA, PhD · Graeme C Miller MB BS, PhD, FRACGP · Christopher Harrison BPsych(Hons), MSocHlth · Margaret A Kelaher PhD, BSc(Psych)

Appropriate use of antibiotics for urinary tract infections is an important consideration for residents in aged care

Lynn M Weekes

Doctors should be aware of an unusual but easily treatable response to statin therapy

Bobak Bahrami MB BS · Saul Rajak PhD, FRCOphth · Dinesh Selva FRACS, FRANZCO

Gaining ethics approval at one ethics committee involves effort, but in multicentre research projects, the effort is multiplied with non-concordant approval requirements

Merin V Pariyadan BPharm(Hons) · Elizabeth D Hotham PhD, MAppSc(Pharm), BPharm · Sean Turner MSc, BPharm · Sanjay Garg PhD, MPharm, MMgt

There is room for improvement in the use of transdermal opioid patches in aged care residents

Svetla Gadzhanova PhD, MSc · Elizabeth E Roughead BPharm, MAppSc, PhD · Lisa G Pont PhD, BPharm, BSc

Metronidazole is a known neurotoxic antibiotic that can be ototoxic, if only rarely

Anthony Rotman MB BS · Philip Michael FRCSEd(ORL-HNS), DLO, MA(ODE) · Michael Tykocinski MD, FRACS · Stephen J O’Leary MB BS, PhD, FRACS

NBOMes are hallucinogenic substances that have recently become available as drugs of misuse

Geoffrey K Isbister BSc, FACEM, MD · Alphonse Poklis PhD · Justin L Poklis BSc · Jeffrey Grice PhD

Despite ongoing progress in basic and preclinical cancer nanomedicine research, arguably the single most important challenge is clinical translation

Zdenka Kuncic FAIP, PhD, BSc(Hons)

Non-pharmacological strategies are an essential part of pain management

Lynn M Weekes

Recommendations for the treatment of paracetamol poisoning have been updated

Angela L Chiew BSc(Med), MB BS, FACEM · John S Fountain MB ChB, MEntr · Andis Graudins MB BS, PhD, FACEM · Geoffrey K Isbister BSc, MD, FACEM · David Reith FRACP, PhD · Nicholas A Buckley BMed, FRACP, MD

Clinical indicators have been widely adopted as a measure of health system performance and quality of care provided to patients

Gillian E Caughey BSc(Hons), PhD · Lisa M Kalisch Ellett BPharm, PhD · Stan Goldstein MB BS, MHA · Elizabeth E Roughead BPharm, MAppSci, PhD

Implementation of precision medicine requires a multidisciplinary and systematic approach

Ingrid Winship MD, FRACP, FACD

We are experiencing an exciting era in the treatment of multiple sclerosis

Simon A Broadley MB ChB, PhD, FRACP · Michael H Barnett MB BS, PhD, FRACP · Mike Boggild MD, MRCP, FRACP · Bruce J Brew MD, FRACP, FAAN · Helmut Butzkueven MB BS, PhD, FRACP · Robert Heard MD, FRCP, FRACP · Suzanne Hodgkinson MB BS, PhD, FRACP · Allan G Kermode MD, FRACP, FRCP · Jeannette Lechner-Scott MD, PhD, FRACP · Richard AL Macdonell MD, FRACP, FAFRM(RACP) · Mark Marriott MB BS(Hons), PhD, FRACP · Deborah F Mason MB ChB, FRACP · John Parratt MB ChB, MD, FRACP · Stephen W Reddel MB BS, PhD, FRACP · Cameron P Shaw MB BS(Hons), FRACP · Mark Slee MB BS, PhD, FRACP · Judith M Spies MB BS, PhD, FRACP · Bruce V Taylor MB BS, MD, FRACP · William M Carroll MB BS, MD, FRACP · Trevor J Kilpatrick MB BS, PhD, FRACP · John King MB BS MD FRACP · Pamela A McCombe MB BS, PhD, FRACP · John D Pollard MB BS, PhD, FRACP · Ernest Willoughby MB ChB, FRACP

Inconsistent Schedule 8 prescription requirements between Australian states and territories create unnecessary complexity for health professionals

Andy C Hua BPharm · Finna Shen BPharm · Xiaoting Ge RN, CCRN

Toxic epidermal necrolysis associated with use of contrast medium (comment on case report)

Lloyd J Ridley MB BS, FRANZCR · Sandhya Limaye PhD, FRACP, FRCPA