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Good's syndrome associated with multiple basal cell carcinomas: a case report

Michelle Wu, Nicole Seebacher and Margit Polcz
Med J Aust || doi: 10.5694/mja2.52093
Published online: 9 October 2023

A 61‐year‐old man of European ancestry (Fitzpatrick skin type II) presented with five large fungating lesions (Box 1). These tumours had been progressively growing over a 12‐month period. The presentation of this patient was delayed as he had initially misattributed the lesions to ingrown hairs. He had no personal or family history of melanoma or non‐melanoma skin cancers. He had no personal medical history of autoimmune conditions, recurrent infections, or immunosuppression.


  • 1 Royal Prince Alfred Hospital, Sydney, NSW
  • 2 University of Oxford, Oxford, United Kingdom
  • 3 University of Sydney, Sydney, NSW



Patient consent: The patient gave written consent for publication.


Competing interests:

No relevant disclosures.

  • 1. Good RA, Varco RL. A clinical and experimental study of agammaglobulinemia. J Lancet 1955; 75: 245‐271.
  • 2. Kelesidis T, Yang O. Good's syndrome remains a mystery after 55 years: a systematic review of the scientific evidence. Clin Immunol 2010; 135: 347‐363.
  • 3. Zaman M, Huissoon A, Buckland M, et al. Clinical and laboratory features of seventy‐eight UK patients with Good's syndrome (thymoma and hypogammaglobulinaemia). Clin Exp Immunol 2019; 195: 132‐138.
  • 4. Griffiths CEM, Barfer J, Bleiker TA, et al; editors. Rook's textbook of dermatology, 4 volume set, 9th ed. Chichester (UK): Wiley Blackwell, 2016.
  • 5. O'Reilly Zwald F, Brown M. Skin cancer in solid organ transplant recipients: advances in therapy and management: part II. Management of skin cancer in solid organ transplant recipients. J Am Acad Dermatol 2011; 65: 263‐279.

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