MJA 218 11 19 June cover

Issues

Volume 218 Issue 11

19 June 2023

News

26 June 2023 Media release Free

Reducing opioid use: new Australian guidelines

New clinical guidelines have been developed by Australian researchers to support doctors in reducing opioid use in their patients. Published in the Medical Journal of Australia, the evidence-based clinical guidelines will help general practitioners with what is known as “opioid deprescribing”. Dr Aili Langford, Associate Professor Danijela Gnjidic and Associate Professor Carl Schneider and their colleagues at the University of Sydney have made eleven recommendations providing advice about when and how opioid deprescribing should be considered, and for which patients. “It is possible to reduce opioid use and harms without worsening pain, whilst maintaining or even improving quality of life. However, pain management should not be one-dimensional,” says Associate Professor Gnjidic. Dr Langford said their work was prompted by concerns that Australia may have been following the United States and Canada where there are rising rates of inappropriate prescription opioid use (here and here). “Pain and pain-related conditions are a leading cause of disability and disease burden globally, with one in five adults aged 45 years and over reporting persistent, ongoing pain,” the authors write. The new guidelines will be vital in providing Australian GPs with support and direction to help curb opioid use in their patients. “General practitioners are well positioned to conduct opioid deprescribing due to their ongoing relationship with patients, opportunities for shared decision making, and ongoing monitoring and management,” Dr Langford said. Dr Langford said it is vital for doctors to plan for deprescribing when initially prescribing opioids. “Opioids can be effective in pain management. However, over the longer-term, the risk of harms may outweigh the benefits,” said Associate Professor Schneider from the School of Pharmacy. “Our guideline group felt it was vital to recommend that health care professionals plan for deprescribing at the point of initiation. “This may involve discussions with patients about the expected duration of therapy, goals of care, potential side effects, safe use, storage and disposal, as well as figuring out when and how these medicines will be reduced or discontinued, if appropriate.”

Sam Hunt

Editor’s choice

19 June 2023 Free

Women and health

This issue of the MJA focuses on the health and wellbeing of women and people with a uterus, from their childhood to older age. Sexual assault, abortion, cancer and alcohol, menopause, and heart disease feature in the articles. Although sexual assault victims can be of any gender, most are female. In a moving and sombre reflection, a forensic physician describes her experience dealing with victims of dating app‐facilitated sexual assault (doi: 10.5694/mja2.51941). We included the contact details of mental health support organisations with the article as its content may be distressing and triggering for some readers. It is horrifying to read that “almost one‐in‐five sexual assaults of children in 2019–2020 were facilitated by technology” and that “[w]hat we have long suspected has been captured — the underside of the iceberg”. The author uses fictional vignettes of a 15‐year‐old boy, a woman, and a mother of a 13‐year‐old girl to illustrate the range of cases she manages. A perspective by Mazza explores the challenges to accessing abortion services in Australia, including structural barriers, such as different abortion laws between the states and territories, differences in gestational limits between jurisdictions, high costs, and differing availability of providers across urban and rural areas (doi: 10.5694/mja2.51979). The author recommends increasing “workforce capacity building and creating a pipeline of providers of abortion services” by “exposure to and education on abortion at all stages of a health care professional's career pathway: while a student, during hospital residency and rotations, [and] during discipline‐based training”. Surgical and medical abortion are health care and women are entitled to choose the appropriate option for them. Information hotlines can assist consumers. Mazza writes that removing restrictions on prescription of mifepristone and misoprostol, allowing other professionals such as nurses to provide medical terminations and vacuum aspirations in selected settings, and providing the option of self‐managed abortions (endorsed by the World Health Organization) will improve access and reduce stigma associated with over‐regulation. The author stresses the importance of the availability of telehealth for sexual and reproductive health, the role of leadership and the need for transparency, arguing that “[r]egional level planning, integration, delivery and accountability need to become a given”. Given that cost is a barrier, it is welcome news that the ACT government has reported recently that women and people with uteruses in Canberra will be able to access free medical and surgical abortions, including people without a Medicare card (https://www.cmtedd.act.gov.au/open_government/inform/act_government_media_releases/yvette‐berry‐mla‐media‐releases/2023/no‐cost‐abortions‐now‐available‐in‐the‐act). It is now up to the other states and territories to follow suit to provide no‐cost access to abortions. Although many women will be aware of risk factors for breast cancer, such as family history, age and breastfeeding, there is little awareness of the role alcohol plays as a risk factor. Grigg and colleagues report on a randomised controlled trial, conducted in a BreastScreen site in Melbourne, of women aged over 40 years attending for their routine breast screening (doi: 10.5694/mja2.51991). They evaluate a brief alcohol intervention animation in improving awareness of alcohol as a risk factor for breast cancer. The authors confirm that awareness is low, finding that 20% of women were aware of alcohol as a risk factor at baseline in both intervention and control arms, which is comparable to what is reported in the literature. By four weeks, a significantly larger proportion of women in the intervention arm versus control identified alcohol as a clear risk factor (65% v 38%). The authors also found that alcohol literacy improved with no change in alcohol consumption. Roche and Bowden in the linked editorial raise concerns that middle‐aged and older women are drinking alcohol more often, and provide possible explanations as to why (doi: 10.5694/mja2.51984). They recommend promoting the awareness of the association between alcohol use and breast cancer risk by using novel settings such as BreastScreen and implementing such strategies on a larger scale. While women traditionally are seen as caring for others and putting themselves last, it is quite surprising that a staggering 85% of Australian women with “bothersome” menopause‐related symptoms are not receiving treatment, as reported by Davis and Magraith (doi: 10.5694/mja2.51981). Their perspective explores what could be contributing to this. They observe that “GPs and specialists mostly lack the skills and confidence in managing menopause”, even though their “research has shown that GPs, gynaecologists and pharmacists understand that some women have severe symptoms that may last many years”, and also that women themselves are “unaware that menopause is associated with bone loss [and] cardiometabolic health”. They provide a useful update on the role of the Women's Health Initiative Study in influencing practice and offer up‐to‐date recommendations for managing menopause and perimenopause, as well as the need for research to explore the impact of menopause on the employment of women. It is well known that there are sex disparities in managing acute coronary syndrome (ACS), with women often diagnosed later than men and less likely to receive evidence‐based treatment (https://insightplus.mja.com.au/2021/35/undertreatment‐of‐acs‐in‐women‐this‐needs‐to‐stop/). The authors of a lessons from practice point out the importance of recognising atypical symptoms underlying ACS, which are common in women (doi: 10.5694/mja2.51974). This is even more important when considering unusual causes of acute myocardial infarction. Papadopoulos and colleagues present the case of a 60‐year‐old woman with spontaneous coronary artery dissection, an uncommon cause of ACS. They state that “[r]ecognising atypical symptoms is particularly important with female patients, who may experience cardiac pain differently … compared with men”. A welcome reminder to consider sex differences in symptom presentation.

Tania Janusic

Perspectives

Medical education

Reflection

Editorial

Research

Substance‐related disorders 19 June 2023 Open Access

A brief intervention for improving alcohol literacy and reducing harmful alcohol use by women attending a breast screening service: a randomised controlled trial

Brief alcohol interventions in diverse clinical settings can reach groups often not recognised as being at risk of harmful drinking

Jasmin Grigg · Victoria Manning · Darren Lockie · Michelle Giles · Robin J Bell · Peta Stragalinos · Chloe Bernard · Christopher J Greenwood · Isabelle Volpe · Liam Smith · Peter Bragge · Dan I Lubman

Research letter

Narrative review

Erratum

19 June 2023 Free

Erratum

McCart Reed AE, Hollway G; Q‐IMPROvE study group; Lakhani S. The Queensland IMplementation of PRecision Oncology in brEast cancer (Q‐IMPROvE) pilot study. Med J Aust 2023; 218: 374–375. https://doi.org/10.5694/mja2.51900. In the fourth paragraph, “Further, one patient had a DPYD variant (rs55886062) that predicts a cardiotoxic response to 5‐fluorouracil‐based chemotherapy” should read “Further, one patient had a DPYD variant (rs55886062) that predicts a toxic response to 5‐fluorouracil‐based chemotherapy.”

Next Issue Volume 219 Issue 1

View more
MJA 219 1 3 July cover
Editor’s choice 3 July 2023 Free

Investing in health and wellbeing at a societal level

Virginia Barbour

Perspectives 5 June 2023 Open Access

Commercial determinants of human rights: for‐profit health care and housing

Jennifer Lacy‐Nichols · Rebecca Bentley · Adam G Elshaug

Medical education 3 July 2023 Lessons from practice Open Access

Field cancerisation and radiotherapy: a case of treatment complications

Sarah K Morton · Selim Ozluer · James Muir

Previous Issue Volume 218 Issue 10

View more
MJA 218 10 5 June cover
Editor’s Choice 5 June 2023 Free

COVID‐19: no longer a global health emergency, now a long term challenge

Virginia Barbour

Perspectives 5 June 2023 Open Access

Access to oral COVID‐19 antivirals in the community: are eligibility criteria and systems ensuring equity?

Nicole L Allard · Jose Canevari · Nick Haslett · Benjamin C Cowie

Perspectives 15 May 2023 Free

Avoiding severe drug hypersensitivity reactions: a case for HLA genotyping for at‐risk patients

Jana Stojanova · Richard O Day · Graeme Suthers

Medical education 5 June 2023 Lessons from practice Open Access

Locally acquired respiratory diphtheria in Australia

Simon Smith · James Stewart · Joshua Hanson · Julian Harris · Fred JJ Chuang · Gavin Quail · Bryan Hawarden · Roshni Lad · Shannon McNee · Benjamin McCartney · Tonia Marquardt · Ian Wilson · Catherine Tacon · Bernard CS Whitfield

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