Issues
Volume 209 Issue 6
News
News briefs
Lung damage in ventilated pre-term infants may vary with gestational age Assisted ventilation is crucial to supporting very pre-term babies, but the treatment often leads to chronic lung disease. While survival of pre-term babies has increased over the past 30 years, rates of chronic lung disease have remained static. Researchers from the Murdoch Children’s Research Institute have found that the type of injury caused by ventilation depends on the gestational age of the lungs. The findings, published in Scientific Reports, suggest that individualised respiratory support could reduce risks to infants. In a study undertaken in lambs, the investigators mapped protein changes in blood plasma following ventilation of lambs born at term, pre-term (less than 32 weeks), and very pre-term (less than 26 weeks). By examining blood samples taken during the first 60 minutes of life, the researchers found significant changes in coagulant and complement protein expression in the pre-term lambs. The researchers noted that these changes indicated the potential for progressive lung injury, and would inhibit the effectiveness of some treatments options, such as surfactant administration. In the study’s next phase, the investigators will examine the changes in the lungs of pre-term human infants. https://www.nature.com/articles/s41598-018-30868-x Natural killers may help keep tuberculosis in check Higher levels of natural killer cells are associated with tuberculosis (TB) latency, according to research by a team including investigators from the University of Queensland and Stanford University School of Medicine, published in Nature. The findings raise the question of whether natural killer cells might play an active role in controlling TB infections. Most TB infections are latent; that is, they are manifested as a clinically asymptomatic, contained state. It is estimated that a quarter of the world’s population has latent TB, and fewer than 10% of latent TB infections eventually progress to an active state. The immune system factors that influence the outcome for an individual, however, are poorly understood. To investigate the immune state underlying latency and how it changes when the disease progresses, the investigators studied a number of human cohorts, combining high-dimensional mass cytometry analysis with an examination of gene expression datasets to identify differences in immune cell populations between uninfected people and those with latent or active TB. They found that latent TB was associated with higher numbers of natural killer cells — white blood cells that kill certain pathogens — with more marked antitoxin responses than uninfected individuals. In people with active infections, natural killer cell levels were lower, but returned to baseline levels when the infection was cured. However, the findings do not establish a causal relationship between natural killer cells and TB latency. Additionally, the authors found that measuring natural killer cell levels can indicate the activity level and burden of TB infection in a patient’s lungs, a finding that could help in assessing disease progression and optimising treatment. https://www.nature.com/articles/s41586-018-0439-x
Cate Swannell
Perspectives
Kidney donation and transplantation in Australia: more than a supply and demand equation
Australia and New Zealand have all the elements of a continuous quality improvement process for kidney allocation
Jeremy R Chapman · John Kanellis
Automatic reporting of estimated glomerular filtration rate in Australia turns 13: re-examining the impact
Evidence shows that eGFR automated reporting in Australia is associated with improvements in awareness, early detection, management and referral of patients with chronic kidney disease
Marie Ludlow · Shilpa Jesudason · David W Johnson
Virtual medicine: how virtual reality is easing pain, calming nerves and improving health
Virtual reality has been used to help treat anxiety, control pain, support physical rehabilitation and distract patients during wound care
Brennan MR Spiegel
Medical education
Massive oxidative haemolysis and renal failure caused by high dose vitamin C
A 54-year-old man, who was diagnosed with metastatic prostate cancer in March 2016, received first-line treatment with docetaxel and degarelix
Matthew J Rees · Madeleine C Strach · Kate Burbury · Kelly-Anne Phillips
Accreditation as a quality improvement tool: is it still relevant?
Despite lack of quantitative hard evidence, accreditation still works, although there is room for improvement
Nesibe Akdemir · David A Ellwood · Theanne Walters · Fedde Scheele
Editorials
Protecting our children from obesity: challenges and opportunities
The reluctance of Australian policy makers to take evidence-based action on childhood obesity is unacceptable
Michael J Moore · Martin McKee · Aimee L Brownbill
Research
Sepsis incidence and mortality are underestimated in Australian intensive care unit administrative data
A reliable and reproducible approach to determining the incidence and mortality rates of sepsis in Australian ICUs is needed
Manon Heldens · Marinelle Schout · Naomi E Hammond · Frances Bass · Anthony Delaney · Simon R Finfer
Disparity of access to kidney transplantation by Indigenous and non-Indigenous Australians
The access of Indigenous patients to kidney transplantation needs to be improved
Namrata Khanal · Paul D Lawton · Alan Cass · Stephen P McDonald
Narrative review
Contemporary approaches to the prevention and management of paediatric obesity: an Australian focus
Curbing the problem of obesity is achievable and can be realised through a combination of smart governance, community initiatives, the support of individual efforts, and clinical leadership
Seema Mihrshahi · Megan L Gow · Louise A Baur
When to initiate dialysis for end-stage kidney disease: evidence and challenges
Optimal care to patients with end-stage kidney disease involves timely referral to a nephrologist and a patient-centred decision to start dialysis
Titi Chen · Vincent WS Lee · David C Harris
Letters
Voluntary assisted dying: time to consider the details
To the Editor:In less than 12 months, voluntary assisted dying (VAD) will become a reality in Victoria. The recent past has seen much passionate debate on both sides of this issue, covering aspects of its impact on society, public health, the law, medicine and an individual’s right to self-determination. Public health interventions have provided our society with significant benefits in many areas; however, for most physicians in clinical practice, our care is focused on each individual patient. To date, little attention has been placed on the implications of VAD for each doctor–patient encounter in which a request is made. For a clinician, the most challenging aspect of VAD now is how to support our patients. How do we balance the fundamentals of our professional and personal beliefs with our clinical and therapeutic responsibilities in practice? The legislation allows doctors the choice to participate in VAD or not; yet, we wonder how we may navigate this therapeutic space. While we believe that directly ending life is a boundary we cannot cross, we also know we cannot abandon our patient at what would clearly be a time of need. Can the doctor–patient relationship survive when electing not to participate? No amount of debate in Parliament will answer this question. We believe we need to derive collective wisdom to craft our compassionate response in this setting — in a considered and thoughtful manner. We believe we must recognise our own distress and anxiety and, nevertheless, remain focused on how we best care for patients. We need to remember our critical role as scientists to learn how to accurately assess, measure and report risks and benefits, to improve care for patients requesting VAD and to inform public health policy. In Victoria, VAD will soon be available. As doctors we must consider our response to our patients and assess the resulting impact on our relationship, here and now. This is a conundrum we had hoped we would never need to face. And it is what keeps us up at night.
Brian H Le · Jennifer Philip
Adverse effects of modified release oxycodone/naloxone in patients with moderate to severe liver impairment
To the Editor: Due to the adverse effects of modified release (MR)-oxycodone/naloxone in patients with moderate to severe liver impairment as a result of advanced cirrhosis or with spontaneous or artificially created portosystemic shunts (Box), its use in this patient population is contraindicated.1 In our clinician roles, we have observed both poor analgesic efficacy and opioid withdrawal in such patients, and similar observations are reported in the literature.2,3 There are clear pharmacological and physiological bases for these outcomes. MR-oxycodone/naloxone is an oral combination opioid analgesic. The naloxone component is subject to a significant first-pass metabolism, and bioavailability is less than 2%.4 The benefit of low level oral bioavailability of naloxone is reduced opioid-induced constipation due to antagonism of opioid receptors in the gut while permitting the desired analgesic opioid effects. The recommended dose of MR-oxycodone/naloxone ranges from 2.5/1.25 mg to 80/40 mg twice daily — the upper limit guiding prescribers to avoid further opioid dose escalation.1 In patients with compensated cirrhosis (mild hepatic impairment) (Box), MR-oxycodone/naloxone may cautiously be prescribed.1 Satisfactory analgesia without significant adverse effects has been observed in selected patients with compensated cirrhosis and pain from hepatocellular cancer.5 In moderate to severe liver impairment, the first-pass (hepatic) metabolism of both medications are markedly but disproportionately reduced, thereby increasing the systemic relative exposure to naloxone (Cmax > 5000% of control) compared with oxycodone (Cmax > 200%).1 The mechanisms are hepatocellular dysfunction and spontaneous portosystemic shunting.3 Artificially created surgical or transjugular intrahepatic portosystemic shunts also reduce hepatic extraction. Hepatic infiltration due to malignancy similarly reduces the liver’s ability to metabolise MR-oxycodone/naloxone effectively.2 The relative increase in exposure to naloxone reduces analgesic efficacy through increased antagonism of opioid pain receptors. Escalating doses of MR-oxycodone/naloxone (or other opioid) may not achieve improved analgesia.2 The relatively high systemic naloxone exposure may also induce opioid withdrawal symptoms.3 Switching from MR-oxycodone/naloxone to oxycodone immediate-release in a patient with hepatic impairment contributed to opioid toxicity due to the sudden loss of the high level systemic naloxone exposure.2 In patients with moderate to severe liver impairment due to advanced cirrhosis or with portosystemic shunts, clinicians should be aware of the contraindication of MR-oxycodone/naloxone. Box – Severity of liver impairment in cirrhosis Liver impairment Clinical features of portal hypertension/portosystemic shunting Biochemical signs Mild Early, compensated cirrhosis No ascites or hepatic encephalopathy Albumin ≥ 35 g/L Bilirubin < 34 μmol/L INR < 1.7 Moderate to severe Advanced, decompensated cirrhosis Portosystemic shunting Presence of: Oesophageal/gastric varices Portal vein thrombosis Ascites Hepatic encephalopathy Hepatorenal syndrome TIPSS Surgical portosystemic shunt Albumin < 35 g/L Bilirubin ≥ 34 μmol/L INR ≥ 1.7 INR = international normalised ratio. TIPSS = transjugular intrahepatic portosystemic shunt.
Venessa Pattullo · Gavin G Pattullo · Simone I Strasser
Careers
"Accidental" GP helping the homeless
Dr Andrew Davies operates Homeless Healthcare, a specialist GP service for people living on the streets of Perth
Cate Swannell
Around the universities and research institutes
Baker Heart and Diabetes Institute has appointed Dr Alex Pinto as head of its new Cardiac Cellular Systems laboratory which aims to determine if pathological changes in cardiac cell networks contribute to heart failure; and whether manipulating the cell network can influence cardiac remodeling to prevent and treat subsequent cardiac disease. Dr Pinto most recently led a research group at the Jackson Laboratory in Bar Harbor, Maine in the US. In addition to his role at the Institute, Dr Pinto has a joint appointment with La Trobe University’s Centre for Cardiovascular Biology and Disease Research, and holds an affiliate position at the Jackson Laboratory — where he will maintain a funded research program — until the end of 2019. Key areas of ongoing research will include determining the plasticity and elasticity of cardiac cell networks in the context of physiological stressors such as obesity and hypertension; determining the molecular and cellular drivers of these processes; and development of unique genetic, computational biology, and imaging approaches to study diverse cell populations in the heart. https://baker.edu.au/news/institute-news/news-alex-pinto Professor Ricky Johnstone has been appointed Executive Director of Cancer Research at the Peter MacCallum Cancer Centre. He will also be the Head of the Sir Peter MacCallum Department of Oncology at the University of Melbourne. Professor Johnstone has been acting in the EDCR role while Peter Mac undertook a global search to fill the position and has demonstrated his ability to lead the research team to high levels of performance. He was originally recruited to Peter Mac almost 18 years ago and has held senior leadership roles within the laboratory research domain for 10 years. As Head of the Gene Regulation Laboratory, Prof Johnstone holds a professorial appointment with the University of Melbourne and was appointed Associate Director Laboratory Research at Peter Mac in 2015. He takes over the role from Professor Joe Trapani who held the EDCR position since 2009. Prof Trapani is continuing to lead Peter Mac’s ground-breaking immunotherapy research in his role as Head of Peter Mac’s Cancer Immunology Program and Group Leader for the Cancer Cell Death Laboratory. https://www.petermac.org/news/new-head-cancer-research-peter-mac Dr Ashleigh Lin, Head of Mental Health and Youth research at the Telethon Kids Institute has won a $716 000 grant from the NHMRC to investigate the social and emotional wellbeing and mental health needs of Aboriginal and Torres Strait Islander young people who identify as lesbian, gay, bisexual, transgender, intersex or queer (LGBTIQ). Her project was one of five chosen following a targeted call by the NHMRC for research into Indigenous Social and Emotional Wellbeing (SEWB). The chosen projects will share in a total of $5.5 million of funding. Dr Lin and fellow Telethon Kids mental health researcher Dr Yael Perry will work with Western Sydney University, the Kulbardi Aboriginal Centre at Murdoch University, and Aboriginal and Torres Strait Islander LGBTIQ suicide prevention not-for-profit Black Rainbow to give a voice to young people whose experiences and needs have until now been poorly understood. Dr Lin said it was difficult to say how many young Aboriginal or Torres Strait Islander people aged 15-24 identified as LGBTIQ, but it was thought the figure likely exceeded 17 000 across Australia. https://www.telethonkids.org.au/news--events/news-and-events-nav/2018/august/research-to-investigate-needs-of-aboriginal-lgbtiq/
Cate Swannell
Calendar of conferences in Australia and New Zealand
This calendar will be updated regularly. If you have an event you would like to add, please include relevant details in an email to cswannell@mja.com.au. The full version of the calendar is available online at https://www.mja.com.au/careers September 17-18 PharmaAus18, Canberra, ACT 17-19 Congress of Aboriginal and Torres Strait Islander Nurses and Midwives, Adelaide, SA 18-19 Consumers Health Forum of Australia Inaugural Youth Health Forum, Canberra, ACT 19-21 23rd Hospice NZ Palliative Care Conference, Auckland, NZ 20-23 Australasian Society of Cosmetic Dermatologists Symposium, Melbourne, VIC 21 Pain Interest Group Nursing Issues Professional Development Day, Sydney, NSW 21 2nd Australasian Neurofibromatosis Conference 2018, Melbourne, VIC 21-23 ANZCA Combined SIG Meeting, Byron Bay, NSW 21-23 RCPA New Zealand Committee of Pathologists ASM 2018, Wellington, NZ 24 The 6th Australian Health Economics Doctoral Workshop, Hobart, TAS 24-26 Australasian HIV and AIDS Conference 2018, Sydney, NSW 25-26 The 40th Annual Australian Health Economics Society Conference, Hobart, TAS 26-28 AIDA Conference 2018: Vision into action, Perth, WA 26-28 Australian Public Health Conference, Cairns, QLD 27-28 National Eating Disorders and Obesity Conference, Tweed Heads, NSW 27-30 2018 Australian Psychological Society Congress, Sydney, NSW 29 Sep-1 Oct Australian and New Zealand Society for Vascular Surgery 2018, Auckland, NZ OCTOBER 2-4 National Aboriginal and Torres Strait Islander Health Worker Association 2018 Symposium, Alice Springs, NT 2-5 SSEM 2018: Peripheral Hospitals Emergency Medicine Conference, Daydream Island, QLD 2-6 32nd International Papillomavirus Conference, Sydney, NSW 4-6 International Society for Hip Arthroscopy 2018 ASM, Melbourne, VIC 5 Quality Improvement Scientific Symposium 2018, Wellington, NZ 5-6 ANZCA Cardiac Thoracic Vascular and Perfusion SIG Meeting, Adelaide, SA 5-6 Australasian Melanoma Conference 2018, Melbourne, VIC 5-7 Australasian Trauma Society 22nd ASM, Perth, WA 6-8 MRI – Upper and Lower Limb Interpretation Workshop 2018, Sydney, NSW 6-9 Australian Society of Anaesthetists National Scientific Congress 2018, Adelaide, SA 7-10 Australian and New Zealand Society of Occupational Medicine (ANZSOM) Annual Scientific Meeting 2018: Perspectives in Occupational Health, Melbourne, VIC 7-11 Australian Orthopaedic Association ASM 2018: Better Patient Outcomes, Perth, WA 8-9 Australia and New Zealand Gastric and Oesophageal Surgery Association and the Australia and New Zealand Hepatic, Pancreatic and Biliary Associated Combined Meeting 2018, Wellington, NZ 10-12 IHF World Hospital Congress 2018, Brisbane, QLD 10-13 Sports Medicine Australia 2018, Perth, WA 11-12 Sydney Cancer Conference, Sydney, NSW 11-13 ANZICS/ACCCN Intensive Care ASM, Adelaide, SA 11-13 Melbourne International Breast Congress, jointly held with the Australasian Society for Breast Disease, 4th World Congress on Controversies in Breast Cancer and Breast Surgeons of Australia and New Zealand, Melbourne, VIC 11-14 RACGP: GP18, Gold Coast, QLD 12 VMIAC Consumer Awards, Brunswick, VIC 12-14 Australasian Military Medicine Association 27th Conference: Armistice to Afghanistan: Evolution of military healthcare, Canberra, ACT 14-17 New Zealand Orthopaedic Association ASM 2018, Rotorua, NZ 15-17 10th Australian Rural and Remote Mental Health Symposium, Hobart, TAS 16-19 71st Annual General and Scientific Meeting of the New Zealand Society of Otolaryngology Head and Neck Surgery, Queenstown, NZ 16-19 Australian and New Zealand Burn Association ASM 2018, Brisbane, QLD 16-19 Australian Association of Practice Management Conference, Canberra, ACT 17-20 Australasian Sleep Association Sleep DownUnder 2018, Brisbane, QLD 17-20 Australasian Society of Cataract and Refractive Surgeons 22nd Annual Conference 2018, Noosa, QLD 17-20 Royal Australian and New Zealand College of Psychiatrists’ Faculty of Child and Adolescent Psychiatry Conference 2018, Perth, WA 18-20 Australian and New Zealand Association of Oral and Maxillofacial Surgeons Annual Meeting 2018, Perth, WA 19 Australasian Diabetes Advancements and Technologies Summit, Sydney, NSW 19-20 2018 RACS Victorian Annual Scientific Meeting, Melbourne, VIC 19-20 Paediatric Society of Queensland Annual Scientific and Educational Meeting, Brisbane, QLD 20-21 Australasian College of Legal Medicine 2018 ASM: Personal injury law, Sydney, NSW 21-24 Combined ASM of the Haematology Society of Australia and New Zealand, the Australian and New Zealand Society of Blood Transfusion and the Thrombosis and Haemostasis Society of Australia and New Zealand, Brisbane, QLD 22-24 Australasian Epidemiological Association 31st ASM, Fremantle, WA 24-26 44th International Mental Health Nursing Conference: Mental health is a human right, Cairns, QLD 24-26 Urological Society of Australia and New Zealand – New Zealand Section Meeting 2018, Palmerston North, NZ 24-27 27th National Conference on Incontinence, Hobart, TAS 24-27 General Practice and Acute Medicine Update Refresher, Melbourne, VIC 25-26 Emergency Nurse Leadership Program, Melbourne, VIC 25-27 ANZCA Perioperative Medicine SIG Meeting, Melbourne, VIC 25-27 Colorectal Surgical Society of Australia and New Zealand and the Colon and Rectal Surgery Section of the RACS Spring Colorectal Meeting 2018, Fremantle, WA 25-28 2018 RANZCR 69th ASM, Canberra, ACT 25-28 Australian College of Rural and Remote Medicine and Rural Doctors Association of Australia: Rural Medicine Australia 2018, Darwin, NT 26 New Zealand Sports Medicine Conference 2018, Nelson, NZ 26-27 Innovations in Rehabilitation and Mental Health Conference, Melbourne, VIC 26-27 2018 RACP Northern Territory ASM: Vulnerable populations, Darwin, NT 26-28 Australian Anaesthesia Allied Health Practitioners 3rd National Conference, Sydney, NSW 27 Alfred Pain Symposium: Opioids: friends or foes, Melbourne, VIC 27-28 Acute Stroke Treatment Seminar, Sydney, NSW 28 Oct-1 Nov Cutaneous Biology 2018, North Stradbroke Island, QLD 31 Oct-2 Nov 20th Australasian Gastro-Intestinal Trials Group ASM 2018, Brisbane, QLD 31 Oct-1 Nov 2nd Annual National NDIS Mental Health Conference, Melbourne, VIC NOVEMBER 1-3 International Union Against Sexually Transmitted Infections Asia Pacific Sexual Health Congress 2018, Auckland, NZ 1-4 General Practice and Acute Medicine Update Refresher, Brisbane, QLD 2 2018 RACP Tasmanian Conference, Burnie, TAS 2-3 Australasian Gynaecological Endoscopy and Surgical Society Focus Meeting, Canberra, ACT 2-3 2018 New Zealand Melanoma Summit, Auckland, NZ 3-4 14th National Laser and Cosmetic Medicine Conference 2018, Brisbane, QLD 4-7 Australasian Genomic Technologies Conference, Glenelg, SA 6-9 5th National Indigenous Drug and Alcohol Conference, Adelaide, SA 7-9 Nepean Blue Mountains Local Health District Together Achieving Better Health Conference, Penrith, NSW 7-9 Paediatric Society of New Zealand 70th ASM 2018, Nelson, NZ 7-9 Australian Association for Adolescent Health 2018 Youth Health Conference, Gold Coast, QLD 7-10 RANZCP Faculty of Psychiatry of Old Age and the Asian Society Against Dementia Conference 2018, Melbourne, VIC 8-10 New Zealand Anaesthesia Annual Scientific Meeting 2018, Auckland, NZ 8-10 RANZCP Faculty of Psychiatry of Old Age and the Asian Society Against Dementia Conference 2018, Melbourne, VIC 9 Health Information Technology, Perth, WA 10-17 2018 IEEE Nuclear Science Symposium and Medical Imaging Conference, Sydney, NSW 11-14 11th International Conference on Frontotemporal Dementias, Sydney, NSW 13-15 Clinical Oncology Society of Australia 2018 ASM, Perth, WA 16-18 General Practice Conference and Exhibition, Melbourne, VIC 17-18 Critical Care Imaging Interpretation 2018, Noosa Heads, QLD 17-21 50th Annual Scientific Congress of the Royal Australian and New Zealand College of Ophthalmologists, Adelaide, SA 18-20 Australian and New Zealand Falls Prevention Society Conference, Hobart, TAS 18-22 Australasian College for Emergency Medicine, 35th ASM, Perth, WA 20-21 Food Futures Conference, Brisbane, QLD 20-21 2nd National Aboriginal and Torres Strait Islander Suicide Prevention Conference, Perth, WA 21-22 2nd Australasian FASD Conference 2018, Perth, WA 21-23 11th Hospital in the Home ASM: LEARN: Lead, engage, aspire, research, negotiate, Brisbane, QLD 21-23 Australian Association of Gerontology Conference 2018, Melbourne, VIC 21-23 New Zealand Society of Gastroenterology ASM 2018, Dunedin, NZ 21-24 6th Asia-Oceanian Conference of Physical and Rehabilitation Medicine combined with the Rehabilitation Medicine Society of Australia and New Zealand's 3rd Annual Scientific Meeting, Auckland, NZ 21-24 Australian and New Zealand Association of Psychiatry, Psychology and Law 2018 Annual Conference: Sins of the past: reflections and future directions, Hobart, TAS 21-24 General Practice and Acute Medicine Update Refresher, Sydney, NSW 22-23 New Zealand Respiratory Conference 2018, Auckland, NZ 22-23 2nd World Indigenous Suicide Prevention Conference, Perth, WA 23 RECOVER Forum 2018: Innovation in rehabilitation, South Brisbane, QLD 23-25 Queensland Hand Surgery Society Conference, Noosa, QLD 23-25 Australia and New Zealand Conference on Sarcopenia and Frailty 2018, Dunedin, NZ 26-28 1st International Motor Impairment Conference, Sydney, NSW 26-29 8th Gathering of Healing Our Spirit Worldwide, Sydney, NSW 27 Osteoarthritis Summit, Canberra, ACT 27 2nd Annual Conference of the Alliance for the Prevention of Mental Disorders, Noosa, QLD 27-28 7th Annual NHMRC Symposium on Research Translation: Ensuring value in research, Sydney, NSW 28-30 40th Annual Society for Mental Health Research Conference: Collaboration, Noosa, QLD 29 Nov-1 Dec ASID New Zealand Annual Meeting, Dunedin, NZ 30 2018 International Indigenous Allied Health Forum, Sydney, NSW DECEMBER 1 Australasian Gynaecological Endoscopy and Surgery Society Pelvic Anatomy Dissection Cadaveric Workshop, Brisbane, QLD 1 RACP South Australian ASM, Adelaide, SA 2-6 Australasian Society for Immunology 47th ASM 2018, Perth, WA 3-4 Stop Domestic Violence Conference, Gold Coast, QLD 4-6 3rd Global Adolescent and Young Adult Cancer Congress, Sydney, NSW 2019 TBA World Congress on Inflammation, Sydney, NSW JANUARY TBA 12th Australasian Conference on Health Informatics and Knowledge Management 14-16 31st Australian Council for Health, Physical Education and Recreation International Conference, Canberra, ACT FEBRUARY TBA The Australian and New Zealand Glaucoma Society ASM 8-10 Australasian College of Sport and Exercise Physicians Annual Scientific Conference, Queenstown, NZ 23 Australasian Faculty of Rehabilitation Medicine NZ Symposium 2019, Waipuna, NZ 25 Feb-1 Mar Leadership and Innovation in Health, Melbourne, VIC MARCH TBA Medical Parents of Australia and New Zealand Conference, Gold Coast, QLD TBA Australasian Academy of Cerebral Palsy and Developmental Medicine 10th Biennial Scientific Conference, Perth, WA 1-2 Australia and New Zealand Strabismus Society Meeting (Squint Club), Parkville, VIC 6-8 International Medicine Society of Australia and New Zealand Autumn Scientific Meeting 2019, Auckland, NZ 7-10 New Zealand Pain Society ASM, Christchurch, NZ 17-20 Perinatal Society of Australia and New Zealand Annual Congress, Gold Coast, QLD 22-24 ASOHNS 69th Annual Scientific Meeting, South Brisbane, QLD 24-27 15th National Rural Health Conference, Hobart, TAS 25-30 International Neuromodulation Society 14th World Congress, Sydney, NSW 25-26 No More Harm National Conference: Bullying, Harassment and Discrimination, Gold Coast, QLD 27-28 9th Annual Australian Healthcare Week, Sydney, NSW 27-30 8th World Glaucoma Congress, Melbourne, VIC 29 Mar-2 Apr Annual Scientific Meetings of The Australia and New Zealand Society of Respiratory Science and The Thoracic Society of Australia and New Zealand, Gold Coast, QLD APRIL 7-10 2019 Australian Pain Society 39th ASM, Gold Coast, QLD 11-13 Biennial meeting of the Asia Pacific Society of Sexual Medicine, Brisbane, QLD 12-15 ISN World Congress of Nephrology 2019, Melbourne, VIC 13-16 Urological Society of Australia and New Zealand 72nd ASM, including the ANZUNS 24th annual meeting, Brisbane, QLD 30 Apr-3 May Australasian College of Emergency Medicine Winter Symposium 2019, Rotorua, NZ MAY TBA RACP Congress 2019, Auckland, NZ 5-7 20th Annual Scientific Meeting of the Australasian College of Phlebology, Cairns, QLD 13-15 Australian and New Zealand Addiction Conference: Prevention, treatment, recovery, Gold Coast, QLD 16-18 ASID Annual Scientific Meeting 2019, Darwin, NT 18-21 Australasian College of Dermatologists Annual Scientific Meeting, Melbourne, VIC 25-30 International Neuromodulation Society 14th World Congress, Sydney, NSW JUNE 17-20 Lowitja Institute International Indigenous Health and Wellbeing Conference, TBC 18-20 Global Health Security 2019, Sydney, NSW 25-28 International Society on Early Intervention Conference 2019: Research to practice in early intervention: an international perspective, Sydney, NSW JULY 27-30 Transplantation Society of Australia and New Zealand PGC and ASM, Sydney, NSW AUGUST 3-6 Human Genetics Society of Australasia 43rd ASM, Wellington, NZ 8-11 67th Annual Scientific Meeting of the Cardiac Society of Australia and New Zealand, Adelaide, SA 9-11 13th Annual Australia and New Zealand Endovascular Therapies Meeting, Adelaide, SA 12-16 17th Deaf Blind International World Conference 2019, Gold Coast, QLD SEPTEMBER 7-8 Rural Dermatology Meeting, Orange, NSW 15-19 14th World Congress on Inflammation, Sydney, NSW 29 Sep-2 Oct 18th Biennial Clinical Neurophysiology Workshop, Gold Coast, QLD OCTOBER TBA RACGP conference, GP19 14-18 World Congress of Intensive Care, Melbourne, VIC 20-23 11th Development Origins of Health and Disease World Congress, Melbourne, VIC NOVEMBER 17-19 10th World Congress of Itch, Sydney, NSW 2020 APRIL 2-4 Exercise and Sports Science Australia Research to Practice 2020, Perth, WA MAY 16-18 Australasian College of Dermatologists Annual Scientific Meeting, Adelaide, SA 2021 NOVEMBER 10-13 XIII International Congress of Dermatology, Melbourne, VIC DECEMBER TBA FIGO World Congress of Gynaecology and Obstetrics, Sydney, NSW
Cate Swannell
News briefs
Cate Swannell
Pathway to ending avoidable diabetes-related amputations in Australia
Peter A Lazzarini · Jaap J van Netten · Robert A Fitridge · Ian Griffiths · Ewan M Kinnear · Matthew Malone · Byron M Perrin · Jenny Prentice · Paul R Wraight
An overview of the GRADE approach and a peek at the future
Waleed Alhazzani · Gordon Guyatt
News briefs
Cate Swannell
Medicare-funded cancer genetic tests: a note of caution
Judy Kirk · Kristine K Barlow-Stewart · Nicola K Poplawski · Margaret Gleeson · Kathy Tucker · Michael Friedlander
Whole genome sequencing provides better diagnostic yield and future value than whole exome sequencing
John S Mattick · Marcel Dinger · Nicole Schonrock · Mark Cowley
Vale New Medical School (the Blackburn Building), University of Sydney
Catherine E Storey