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An overview of the GRADE approach and a peek at the future

Waleed Alhazzani and Gordon Guyatt
Med J Aust 2018; 209 (7): 291-292. || doi: 10.5694/mja18.00012
Published online: 1 October 2018

The Grading of Recommendations Assessment, Development and Evaluation approach provides a clear interpretation of the quality of evidence for key stakeholders

In 2004, a group of international experts in methodology and practice guidelines first published the Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach1 to assess the quality of evidence supporting medical interventions and develop recommendations. Since then, the group has published a six-part series for clinicians using GRADE guidelines,2 and a series of articles supporting systematic review authors and guideline groups using GRADE in their work.3

  • Waleed Alhazzani
  • Gordon Guyatt

  • McMaster University, Hamilton, Canada


Competing interests:

Waleed Alhazzani and Gordon Guyatt are owners of MetaClinician. Gordon Guyatt is a consultant for UpToDate.

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