Australia has one of the highest rates of inflammatory bowel disease (IBD) in the world; its prevalence has increased significantly over the past 20 years and is projected to increase by > 250% from 2010 to 2030, to then affect 1% of the population.1 Although advances in clinical practice have led to increased identification, this increase is thought to be due to urbanisation of communities, with changes in sanitation and dietary practices. Such changes seen in Asia over the past 20 years have mirrored the rapidly increasing rates of IBD in the Western society, lending support to the “hygiene hypothesis”, and explaining, in part, the increasing burden of IBD on Australian health care due to our high rates of immigration.1,2
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- 1. Kaplan GG, Windsor JW. The four epidemiological stages in the global evolution of inflammatory bowel disease. Nat Rev Gastroenterol Hepatol 2021; 18: 56‐66.
- 2. Mak W, Zhao M, Ng S, Burisch J. The epidemiology of inflammatory bowel disease: east meets west. J Gastroenterol Hepatol 2020; 35: 380‐389.
- 3. Phavichitr N, Cameron D, Catto‐Smith A. Increasing incidence of Crohn's disease in Victorian children. J Gastroenterol Hepatol 2003; 18: 329‐332.
- 4. Schildkraut V, Alex G, Cameron D, et al. Sixty‐year study of incidence of childhood ulcerative colitis finds eleven‐fold increase beginning in 1990s. Inflamm Bowel Dis 2013; 19: 1‐6.
- 5. Grover Z. Predicting and preventing complications in children with inflammatory bowel disease. Transl Pediatr 2019; 8: 70‐76.
- 6. Perler BK, Ungaro R, Baird G, et al. Presenting symptoms in inflammatory bowel disease: descriptive analysis of a community‐based inception cohort. BMC Gastroenterol 2019; 19: 1‐8.
- 7. Ozer M, Bengi G, Colak R, et al. Prevalence of irritable bowel syndrome‐like symptoms using Rome IV criteria in patients with inactive inflammatory bowel disease and relation with quality of life. Medicine (Baltimore) 2020; 99: e20067.
- 8. Menees S, Powell C, Kurlander J, et al. A meta‐analysis of the utility of C‐reactive protein, erythrocyte sedimentation rate, fecal calprotectin, and fecal lactoferrin to exclude inflammatory bowel disease in adults with IBS. Am J Gastroenterol 2015; 110: 444‐454.
- 9. Item 66522. Medicare Benefits Schedule 2023 [website]. https://www9.health.gov.au/mbs/fullDisplay.cfm?type=item&q=66522&qt=ItemID (viewed June 2024).
- 10. Maaser C, Sturm A, Vavricka SR, et al. ECCO‐ESGAR guideline for diagnostic assessment in IBD part 1: initial diagnosis, monitoring of known IBD, detection of complications. J Crohns Colitis 2019; 13: 144‐164.
- 11. Ward M, Kariyawasam V, Mogan S, et al. Prevalence and risk factors for functional vitamin B12 deficiency in patients with Crohn's disease. Inflamm Bowel Dis 2015; 21: 2839‐2847.
- 12. Akbulut S. An assessment of serum vitamin B12 and folate in patients with Crohn's disease. Medicine (Baltimore) 2022; 101: e31892.
- 13. Caviezel D, Maissen S, Niess J, et al. High prevalence of vitamin D deficiency among patients with inflammatory bowel disease. Inflamm Intest Dis 2018; 2: 200‐210.
- 14. Alper A, Zhang L, Pashankar D. Correlation of erythrocyte sedimentation rate and C‐reactive protein with pediatric inflammatory bowel disease activity. J Pediatr Gastroenterol Nutr 2017; 65: e25‐27.
- 15. Srinivasan A, Cruz PD. Review article: a practical approach to the clinical management of NSAID enteropathy. Scand J Gastroenterol 2017; 52: 941‐947.
- 16. Surawicz C. What's the best way to differentiate infectious colitis (acute self‐limited colitis) from IBD? Inflamm Bowel Dis 2008; 14 Suppl 2: S157‐158.
- 17. Gazelakis K, Chu I, Martin C, et al. P320 thrombocytosis in acute inflammatory bowel disease: a useful biomarker? J Crohns Colitis 2020; 14 Suppl 1: S313‐314.
- 18. Fernandes S, Vasconcelos‐Castro S, Teixeira C, Soares‐Oliveira M. Yersinia enterocolitis may mimic appendicitis: 12 years of experience in a single tertiary center. GE Port J Gastroenterol 2020; 28: 26‐31.
- 19. Mellander MR, Ekbom A, Hultcrantz R, et al. Microscopic colitis: a descriptive clinical cohort study of 795 patients with collagenous and lymphocytic colitis. Scand J Gastroenterol 2016; 51: 556‐562.
- 20. Hung A, Calderbank T, Samaan M, et al. Ischaemic colitis: practical challenges and evidence‐based recommendations for management. Frontline Gastroenterol 2019; 12: 44‐52.
- 21. Cassieri C, Brandimarte G, Elisei W, et al. How to differentiate segmental colitis associated with diverticulosis and inflammatory bowel diseases. J Clin Gastroenterol 2016; 50 Suppl 1: S36‐38.
- 22. Hatemi I, Hatemi G, Çelik A. Systemic vasculitis and the gut. Curr Opin Rheumatol 2017; 29: 33‐38.
- 23. Skef W, Hamilton M, Arayssi T. Gastrointestinal Behçet's disease: a review. World J Gastroenterol 2015; 21: 3802‐3812.
- 24. Australian Bureau of Statistics. Permanent migrants in Australia. Mar 2023. https://www.abs.gov.au/statistics/people/people‐and‐communities/permanent‐migrants‐australia/latest‐release (viewed July 2023).
- 25. Choudhury A, Dhillon J, Sekar A, et al. Differentiating gastrointestinal tuberculosis and Crohn's disease – a comprehensive review. BMC Gastroenterol 2023; 23: 246.
- 26. King J, McManus H, Kwon J, et al. HIV, viral hepatitis and sexually transmissible infections in Australia: annual surveillance report 2022. Sydney: The Kirby Institute, UNSW, 2022. Chrome‐extension://efaidnbmnnnibpcajpcglclefindmkaj/ https://www.kirby.unsw.edu.au/sites/default/files/documents/Annual‐Surveillance‐Report‐2022_HIV.pdf (viewed July 2023).
- 27. Di Altobrando A, Tartari F, Filippini A, et al. Lymphogranuloma venereum proctitis mimicking inflammatory bowel diseases in 11 patients: a 4‐year single‐center experience. Crohns Colitis 360 2019; 1:otz004.
- 28. Sheibani S, Gerson L. Chemical colitis. J Clin Gastroenterol 2008; 42: 115‐121.


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Mark Ward has received educational grants and speaker fees from AbbVie, Takeda and Ferring; travel grants from Pfizer; and has served on advisory boards for AbbVie.