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Towards national paediatric clinical practice guidelines
Kelvin Hill · Steven McGloughlin · Sharon McGowan · Tari Turner
Long COVID in Victoria
Almost five years into the COVID-19 pandemic, there are still major gaps in our knowledge as to the pathophysiology, treatment and prognosis of long COVID
David A Watters · Lance Emerson
Persistent symptoms after COVID‐19: an Australian stratified random health survey on long COVID
Improved community understanding of long COVID is required, and health systems need to develop clear pathways for treating patients, especially for those with persistent impairment
Alex Holmes · Lance Emerson · Louis B Irving · Emma Tippett · Jeffrey M Pullin · Julie Young · David A Watters · Adina Hamilton
Factors associated with general practitioner‐led diagnosis of long COVID: an observational study using electronic general practice data from Victoria and New South Wales, Australia
Identification of predisposing risk factors is essential to inform early intervention and management strategies for patients at greatest risk of long COVID
Abbish Kamalakkannan · Mirela Prgomet · Judith Thomas · Christopher Pearce · Precious McGuire · Fiona Mackintosh · Andrew Georgiou
Changes in the incidence of type 2 diabetes in Australia, 2005–2019, overall and by socio‐demographic characteristics: a population‐based study
The incidence of type 2 diabetes in Australian adults declined during 2010–2019 across all age, sex, socio-economic disadvantage, and remoteness groups
Dianna J Magliano · Lei Chen · Jedidiah I Morton · Oyunchimeg Buyadaa · Agus Salim · Jonathan E Shaw
Adherence to clinical care standards and mortality after hip fracture surgery in New South Wales, 2015–2018: a retrospective population‐based study
High level acute clinical care, provided for about two-thirds of hip fractures, was associated with lower short and longer term mortality
Lara Harvey · Morag E Taylor · Ian A Harris · Rebecca J Mitchell · Ian D Cameron · Pooria Sarrami · Jacqueline Close
Implementability and impact in clinical research and the role of clinical trial networks
A framework for planning, design and reporting of clinical trials, to optimise implementability
Helena J Teede · Karen Best · Frank H Bloomfield · Alan Cass · Paul Cohen · Sue Crengle · Tiffany Harris‐Brown · Stephen Jan · David W Johnson · Samantha Keogh · Anne McKenzie · Philippa Middleton · Sandra Peake · Hashim Periyalil · Paul A Scuffham · Angela Scheppokat · Greg R Sharplin · Steve Webb
Holistic support framework for doctors training as rural and remote general practitioners: a realist evaluation of the RVTS model
Understanding how to deliver holistic supervision and support for the challenges doctors face when training as general practitioners in rural, remote and First Nations communities, can support interventions which build personal and professional resilience for rural practice
Belinda G O'Sullivan · Patrick Giddings · Ronda Gurney · Matthew R McGrail · Tiana Gurney
Perceived stakeholder benefits of continuously training general practitioners in the same rural or remote practice: interviews exploring the Remote Vocational Training Scheme
The RVTS model of training doctors continuously in the same practice improves access to safe and high quality longitudinal care and contributes to service enhancements in rural, remote and First Nations communities that otherwise lack stable doctors
Belinda G O'Sullivan · Patrick Giddings · Matthew R McGrail
Summary of the 2023 international evidence‐based guideline for the assessment and management of polycystic ovary syndrome: an Australian perspective
The 2023 International evidence-based guideline for the assessment and management of polycystic ovary syndrome provides updated evidence-based recommendations for the clinical assessment and management of polycystic ovary syndrome
Helena J Teede · Aya Mousa · Chau T Tay · Michael F Costello · Leah Brennan · Robert J Norman · Alexia S Pena · Jacqueline A Boyle · Anju Joham · Lorna Berry · Lisa Moran
Recommendations from the 2024 Australian evidence‐based guideline for unexplained infertility: ADAPTE process from the ESHRE evidence‐based guideline on unexplained infertility
If we are to offer accessible, equitable, cost-effective fertility services to people who desire a child, we need to align to best practice evidence
For the Australian NHMRC Centre for Research Excellence in Reproductive Life UI Guideline Network and the ESHRE guideline group for unexplained infertility
Pharmaceuticals in pregnancy: a multifaceted challenge in Australia
Pregnant women face barriers to pharmaceutical trial participation, and a conservative drug safety categorisation system
Stefan C Kane · Renuka Shanmugalingam · Amanda Henry
Policies on the collection, analysis, and reporting of sex and gender in Australian health and medical research: a mixed methods study
Research policy and guidelines for integrating sex and gender into health and medical research must be implemented and evaluated to achieve change
Cheryl Carcel · Amy Vassallo · Laura Hallam · Janani Shanthosh · Kelly Thompson · Lily Halliday · Jacek Anderst · Anthony KJ Smith · Briar L McKenzie · Christy E Newman · Keziah Bennett‐Brook · Zoe Wainer · Mark Woodward · Robyn Norton · Louise Chappell
Changes in the incidence of melanoma in Australia, 2006–2021, by age group and ancestry: a modelling study
Migration may have reduced the incidence of melanoma among younger Australians, but social changes may also have contributed
David C Whiteman · Rachel E Neale · Peter Baade · Catherine M Olsen · Nirmala Pandeya
The impact of ageing‐in‐place reforms on the provision of home care packages for older Australians, 2008–21: a repeated cross‐sectional study
Meeting demand for higher care level support will require a larger aged care workforce particularly in regional and remote areas
Johannes Schwabe · Gillian E Caughey · Steve L Wesselingh · Craig Whitehead · Renuka Visvanathan · Keith Evans · Maria C Inacio
Understanding modelled economic evaluations: a reader's guide for clinicians
The role of modelled versus study-based economic evaluations, and an introduction to common modelling approaches
Winnie Chen · Martin Howell · Alan Cass · Gillian Gorham · Kirsten Howard
The public health and economic burden of long COVID in Australia, 2022–24: a modelling study
The health and economic burdens of long COVID are substantial, especially for working adults
Valentina Costantino · Quentin Grafton · Tom Kompas · Long Chu · Damian Honeyman · Adriana Notaras · C Raina MacIntyre
The Alfred Health post‐COVID‐19 service, Melbourne, 2020–2022: an observational cohort study
To the Editor: Holland and colleagues reported on the Alfred Health post‐COVID‐19 service experience with the health of patients who had previously been hospitalised, or managed in a hospital‐in‐the‐home setting, with COVID‐19.1 Participants responded to an invitation to register for follow‐up, and then completed a questionnaire. The study also included a separate group (13% of the cohort) who were not necessarily admitted to Alfred Health but lived in the Alfred Health catchment — and might have been managed as outpatients or inpatients in another service but were referred by their local doctors to a specialist clinic targeted for patients with symptoms after initial COVID‐19, and subsequently completed the questionnaire. Sixty per cent of respondents had at least one persistent symptom at eight weeks. The study reported apparently high prevalences of other symptoms, such as post‐traumatic stress disorder in 23%. These results are derived from their cohort and may not be generally applicable. The authors caution: “We could not distinguish between new symptoms and those attributable to other health conditions. Our study did not include a contemporary control group”.1 More importantly, there was no control group of patients hospitalised from non‐COVID‐19 viral illness (with sufficient severe illness to lead to almost 5% spending time in an intensive care unit), who were then concentrated by an invitation, and then sufficiently motivated to fill out a questionnaire. Plausibly in such a group, at eight weeks, 60% would report at least one persistent symptom. Interpretation of their results is also obscured by the patients referred from the community, who came from a bigger population of patients with COVID‐19 concentrated to include only those who sought or agreed to a referral to a specialist follow‐up clinic. The authors wisely identified weaknesses and they should be applauded for their review of their experience. More definitive conclusions about higher rates of persisting ill health caused by COVID‐19 (in comparison to similarly severe infectious illness) might be achieved if they can follow this up — as they perhaps recognise — with a prospective analytic design in a cohort of patients presenting with similar severity of viral illness comparing those with and without COVID‐19 over the long term.
Jeremy L Millar
Indigenous governance, ethics and data collection in Australian clinical registries
Aboriginal and Torres Strait Islander communities remain invisible in data which is used to inform policy, clinical models of care, health services and initiatives
Courtney Ryder · Sadia Hossain · Leanne Howard · Julia Severin · Rebecca Ivers
National pharmacovigilance of seasonal influenza vaccines in Australia
Australia’s national pharmacovigilance systems work collaboratively to monitor the safety of seasonal influenza vaccines, with improvements to these systems ensuring the continued safety of medicines and vaccines available on the Australian market
Megan O'Moore · Belinda Jones · Megan Hickie · Catherine Glover · Lucy Deng · Yuanfei Huang · Michael Dymock · Evelyn Tay · Julie A Marsh · Nicholas Wood
Multiple myeloma incidence, mortality, and prevalence estimates and projections, Australia, 1982–2043: a statistical modelling study
In view of the projected increase in disease burden, further research into prevention and early detection is needed
Qingwei Luo · Deanne Jenkin · Marianne F Weber · Julia Steinberg · Kate White · Adam Irving · Hannah Rillstone · Anna Kelly · Karen Canfell · Eleonora Feletto
Living evidence syntheses: the emerging opportunity to increase evidence‐informed health policy in Australia
Living evidence syntheses are critical for evidence-informed policy; however, their use is not as straightforward as providing policy makers with summarised results from research studies
Samantha P Chakraborty · Alex Collie · Rebecca Hodder · Suman S Majumdar · Kim Sutherland · Bernie Towler · Joshua Vogel · Andrew Wilson · Luke Wolfenden · Sally Green · Tari Turner
Contextualising the benefits and risks of anti‐amyloid therapy for patients with Alzheimer disease and their care team
Novel anti-amyloid therapies have generated hope in Alzheimer disease. Although the therapies are generally well tolerated, there are important side effects that need consideration
Oneil G Bhalala · Jane Thompson · Rosie Watson · Nawaf Yassi