Topics
Cancer
Measurement of digoxin levels falsely affected by enzalutamide
A 75-year-old man presented with three days of lethargy and diarrhoea
Noor Lammoza · Maria Hormiz · Cherie Chiang · Chris Stead · Mustafa Ayhan · Samuel C Hume
PEG‐GCSF‐induced aortitis in a patient with breast cancer: distinguishing between infective and immune‐mediated aortitis
A 64-year-old woman presented with non-neutropenic fever and back pain one day after the first cycle of neoadjuvant chemotherapy
Luigi Zolio · Prudence A Francis · Nava Ferdowsi
Contemporary management of advanced colorectal cancer: the Australian experience
The treatment of colorectal cancer has evolved dramatically in the 21st century, particularly for patients with advanced disease
Kilian GM Brown · Nabila Ansari · Michael J Solomon
Immune checkpoint inhibitor therapy for advanced cutaneous squamous cell carcinoma in Australia: a retrospective real world cohort study
ICI therapy could benefit a broader range of people with advanced CSCC than are eligible for clinical trials
Luke S McLean · Annette M Lim · Mathias Bressel · Jenny Lee · Rahul Ladwa · Alexander D Guminski · Brett Hughes · Samantha Bowyer · Karen Briscoe · Samuel Harris · Craig Kukard · Rob Zielinski · Muhammad Alamgeer · Matteo Carlino · Jeremy Mo · John J Park · Muhammad A Khattak · Fiona Day · Danny Rischin
Setting the policy agenda for cancer control reform: Australia's first national cancer control plan
The Australian Cancer Plan is a landmark national policy reform to achieve equity of cancer outcomes and experiences for all Australians
Daniel Chaji · Anna Boltong · Carolyn Der Vartanian · Adam Lambert · Cindy Toms · Vivienne Milch · Claire Howlett · Dorothy Keefe
Human pulmonary dirofilariasis: an unexpected differential diagnosis for a solitary lung lesion
A 56-year-old woman of European ancestry from a suburban area of Far North Queensland was referred to the local cardiothoracic unit for a right lower lobe lung lesion
Sigrid G Theodore · Hannah J Sawkins · Manish Mathew · Sumit Yadav · Robert Norton
The complex impact of COVID‐19 on cancer outcomes in Australia
The pandemic’s ultimate impact on cancer outcomes is likely to be multifaceted
Karen Canfell · Karen Chiam · Carolyn Nickson · G Bruce Mann
The importance of early breast cancer treatment: delay can be deadly
The study by Kou and colleagues provides support for the current Cancer Australia breast cancer treatment guidelines
Nicholas R Wilcken
Health care service use by people diagnosed with invasive melanoma in Queensland: a benefit incidence analysis
Residential location does not markedly influence access to health services for Queenslanders with melanoma
Daniel Lindsay · David C Whiteman · Catherine M Olsen · Louisa G Gordon
Hepatocellular carcinoma surveillance in Australia: current and future perspectives
Hepatocellular carcinoma is a leading cause of cancer-related death worldwide, and is increasing in incidence in Australia
Samuel Hui · Sally Bell · Suong Le · Anouk Dev
Psychosocial outcomes and health service use after notifying women participating in population breast screening when they have dense breasts: a BreastScreen Queensland randomised controlled trial
Robust evidence is needed for future mammography population screening practice and policy
Brooke Nickel · Nick Ormiston‐Smith · Lisa Hammerton · Erin Cvejic · Paul Vardon · Zoe Mcinally · Paula Legerton · Karen Baker · Jennifer Isautier · Emma Larsen · Michelle Giles · Meagan E Brennan · Kirsten J McCaffery · Nehmat Houssami
Field cancerisation and radiotherapy: a case of treatment complications
Gerald B Fogarty · Elizabeth J Paton · David Christie
Field cancerisation and radiotherapy: a case of treatment complications
James Muir · Sarah K Morton · Selim Ozluer
Treatment intervals and survival for women diagnosed with early breast cancer in Queensland: the Breast Cancer Outcomes Study, a population‐based cohort study
Findings support the treatment timeframes recommended as timely in the 2020 guidelines
Kou Kou · Joanne F Aitken · Christopher Pyke · Suzanne Chambers · Jeff Dunn · Peter D Baade
Lung cancer screening for Aboriginal and Torres Strait Islander peoples: an opportunity to address health inequities
A commitment to culturally appropriate codesign processes will shape the development of an equitable lung cancer screening pathway
Alison Brown · Gail Garvey · Nicole M Rankin · Claire Nightingale · Lisa J Whop
Ethical implications of changing the eligibility criteria for the proposed National Lung Cancer Screening Program
To the Editor: The incidence of lung cancer and the five‐year survival of patients diagnosed with lung cancer reflect the social gradient within the Australian society. Most notably, Aboriginal and Torres Strait Islander people are twice as likely to develop lung cancer and half as likely to survive lung cancer.1 Reducing inequity in lung cancer outcomes was a key objective of Cancer Australia when it proposed a National Lung Cancer Screening Program (NLCSP) in 2020, following an enquiry that consulted both medical experts and the broader community.1 The Department of Health sought funding for Cancer Australia's proposed NLCSP in the 2021–2022 Budget but was required by the Department of Finance to refer the proposal to the Medical Services Advisory Committee (MSAC) for review.2 So, when MSAC recently announced its support for the creation of the NLCSP, there was great relief within the lung cancer community. However, what few people seemed to realise was that MSAC had in fact designed, then endorsed, their own alternative model for an NLCSP.3 MSAC's model is fundamentally different to Cancer Australia's model in terms of who is eligible to be screened and, therefore, who can benefit from the screening program. Whereas Cancer Australia intended using an individual's risk of lung cancer (as estimated by the PLCOm2012 risk calculator, which combines sociodemographic data and smoking history),4 MSAC recommended using fixed cut‐offs for age and smoking history. This is problematic in terms of both the evidence base that should have guided MSAC's decision and the ethical implications of the decision. MSAC's approach aligns with the design of historical lung cancer screening trials but it ignores an extensive body of evidence, including both a priori and post hoc analyses of trial data that consistently demonstrate that risk calculators are more efficient than fixed criteria.5 Furthermore, it also ignores international trends in the design of lung cancer screening trials and the implementation of lung cancer screening programs.1 But more importantly, the inevitable consequence of applying MSAC's eligibility criteria will be that fewer socially disadvantaged individuals will be eligible to participate in the NLCSP. This has the potential to exacerbate the existing inequity.
Jonathon B Ryan
Current and emerging medications for the management of obesity in adults
Joshua M Inglis · Ganessan Kichenadasse · Arduino A Mangoni
Current and emerging medications for the management of obesity in adults
Rosalind Walmsley · Priya Sumithran
Patterns of care for people with small cell lung cancer in Victoria, 2011–19: a retrospective, population‐based registry data study
A national registry of SCLC-specific management and outcomes data could improve the quality and safety of care
Joanna Huang · Wasek Faisal · Margaret Brand · Shantelle Smith · Marliese Alexander · Lisa Briggs · Matthew Conron · Mary Duffy · Thomas John · David Langton · Jacqueline Lesage · Michael MacManus · Paul Mitchell · Inger Olesen · Phillip Parente · Jennifer Philip · Evangeline Samuel · Javier Torres · Craig R Underhill · John R Zalcberg · Susan Harden · Rob Stirling
Supporting health care providers in cancer screening: the role of the National Cancer Screening Register
The NCSR improves health care provider engagement in cancer screening through better access to patient screening records and by facilitating safety net follow up of screen-detected abnormalities, which could influence better health outcomes through early detection and treatment
Dorota Gertig · John Lee
Field cancerisation and radiotherapy: a case of treatment complications
A 62-year-old man with a more than 30-year history of actinic keratoses and keratinocyte carcinomas presented for ongoing management
Sarah K Morton · Selim Ozluer · James Muir
Suboptimal experiences with out‐of‐pocket costs, financial disclosure, and support information among people treated for cancer
Health care policy and clinical practice should be revised to support more consistent financial disclosure and support
Victoria White · Karla Gough · Colin Wood · Raymond Chan · Michael Jefford
A brief intervention for improving alcohol literacy and reducing harmful alcohol use by women attending a breast screening service: a randomised controlled trial
Brief alcohol interventions in diverse clinical settings can reach groups often not recognised as being at risk of harmful drinking
Jasmin Grigg · Victoria Manning · Darren Lockie · Michelle Giles · Robin J Bell · Peta Stragalinos · Chloe Bernard · Christopher J Greenwood · Isabelle Volpe · Liam Smith · Peter Bragge · Dan I Lubman