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Anti‐MDA‐5‐positive amyopathic dermatomyositis with cutaneous ulcerations

Yanjun Chen, Gim Gee Teng and Winnie ZY Teo
Med J Aust 2021; 215 (1): . || doi: 10.5694/mja2.51099
Published online: 5 July 2021

A 78‐year‐old woman presented with a recurrent painful ulcerating rash on her hands. She had cutaneous ulcerations over Gottron papules on the first metacarpophalangeal joints of both hands (Figure, A) and a tender rash over the palmar surface with ulcerations of the skin over the fingertips (Figure, B). Motor power was preserved and creatine kinase and aldolase levels were normal. Tests for anti‐melanoma differentiation‐associated protein 5 (MDA‐5) and anti‐Ro‐52 autoantibodies returned positive and she was diagnosed with anti‐MDA‐5‐positive amyopathic dermatomyositis.

  • Yanjun Chen
  • Gim Gee Teng
  • Winnie ZY Teo

  • Alexandra Hospital, National University Health System, Singapore


Correspondence: yanjun_chen@nuhs.edu.sg

Competing interests:

No relevant disclosures.

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