Anti‐MDA‐5‐positive amyopathic dermatomyositis with cutaneous ulcerations

Yanjun Chen, Gim Gee Teng and Winnie ZY Teo
Med J Aust 2021; 215 (1): . || doi: 10.5694/mja2.51099
Published online: 5 July 2021

A 78‐year‐old woman presented with a recurrent painful ulcerating rash on her hands. She had cutaneous ulcerations over Gottron papules on the first metacarpophalangeal joints of both hands (Figure, A) and a tender rash over the palmar surface with ulcerations of the skin over the fingertips (Figure, B). Motor power was preserved and creatine kinase and aldolase levels were normal. Tests for anti‐melanoma differentiation‐associated protein 5 (MDA‐5) and anti‐Ro‐52 autoantibodies returned positive and she was diagnosed with anti‐MDA‐5‐positive amyopathic dermatomyositis.

  • Alexandra Hospital, National University Health System, Singapore


Competing interests:

No relevant disclosures.

  • 1. Bailey EE, Fiorentino DF. Amyopathic dermatomyositis: definitions, diagnosis, and management. Curr Rheumatol Rep 2014 Dec; 16: 465.


remove_circle_outline Delete Author
add_circle_outline Add Author

Do you have any competing interests to declare? *

I/we agree to assign copyright to the Medical Journal of Australia and agree to the Conditions of publication *
I/we agree to the Terms of use of the Medical Journal of Australia *
Email me when people comment on this article

Online responses are no longer available. Please refer to our instructions for authors page for more information.