Progressive multifocal leukoencephalopathy: a complication of prolonged immunosuppression for plasma cell myeloma

Sophie C Burn and Akash Kalro
Med J Aust 2021; 215 (10): . || doi: 10.5694/mja2.51315
Published online: 15 November 2021

A 66‐year‐old man presented to a tertiary emergency department following a fall. He had a 6‐month history of agitation, personality change, progressive cognitive impairment, dysarthria, dysphagia and recurrent falls. On examination, there was proximal muscle wasting and weakness, brisk reflexes and an upgoing plantar reflex on the left foot. Cranial nerve examination was normal.

  • Sophie C Burn
  • Akash Kalro

  • Central Adelaide Local Health Network, Adelaide, SA


Competing interests:

No relevant disclosures.


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