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Coronary artery calcium scoring in cardiovascular risk assessment of people with family histories of early onset coronary artery disease

Andrew Hayen, Paul P Glasziou and Jenny A Doust
Med J Aust 2021; 214 (9): . || doi: 10.5694/mja2.51037
Published online: 17 May 2021

To the Editor: Improving our understanding of the place of computed tomography (CT) coronary calcium scoring in the assessment of cardiovascular disease risk is critical. However, we disagree with the conclusions in the article by Venkataraman and colleagues1 that the results of their study support the use of CT coronary calcium scoring in individuals with intermediate risk using the Australian cardiovascular disease risk (ACVDR) calculator. Unfortunately, the study has significant flaws in its outcome measures — CT coronary artery calcium scoring and Multi‐Ethnic Study of Atherosclerosis (MESA) — which result in misleading conclusions.

  • Andrew Hayen1
  • Paul P Glasziou2
  • Jenny A Doust3

  • 1 University of Technology Sydney, Sydney, NSW
  • 2 Centre for Research in Evidence‐Based Practice, Bond University, Gold Coast, QLD
  • 3 Centre for Longitudinal and Life Course Research, University of Queensland, Brisbane, QLD


Correspondence: andrew.hayen@uts.edu.au

Competing interests:

No relevant disclosures.

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