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To exercise or not to exercise in chronic fatigue syndrome? No longer a question

Andrew R Lloyd
Med J Aust 2004; 180 (9): . || doi: 10.5694/j.1326-5377.2004.tb06016.x
Published online: 3 May 2004

Graded physical exercise is no panacea, but is beneficial


  • Inflammation Research Unit, School of Medical Sciences, University of New South Wales, Kensington, NSW.


Correspondence: 

  • 1. Afari N, Buchwald D. Chronic fatigue syndrome: a review. Am J Psychiatry 2003; 160: 221-236.
  • 2. Fukuda K, Straus SE, Hickie I, et al. The chronic fatigue syndrome: a comprehensive approach to its definition and study. Ann Intern Med 1994; 121: 953-959.
  • 3. Reeves WC, Lloyd A, Vernon SD, for the International Chronic Fatigue Syndrome Study Group. Identification of ambiguities in the 1994 chronic fatigue syndrome research case definition and recommendations for resolution. BMC Health Serv Res 2003; 3: 25.
  • 4. Wessely S, Chalder T, Hirsch S, et al. The prevalence and morbidity of chronic fatigue and chronic fatigue syndrome: a prospective primary care study. Am J Public Health 1997; 87: 1449-1455.
  • 5. Whiting P, Bagnall AM, Sowden AJ, et al. Interventions for the treatment and management of chronic fatigue syndrome: a systematic review. JAMA 2001; 286: 1360-1368.
  • 6. Fulcher KY, White PD. Randomised controlled trial of graded exercise in patients with the chronic fatigue syndrome. BMJ 1997; 314: 1647-1652.
  • 7. Powell P, Bentall RP, Nye FJ, Edwards RHT. Randomised controlled trial of patient education to encourage graded exercise in chronic fatigue syndrome. BMJ 2001; 322: 1-5.
  • 8. Wearden A, Morris R, Mullis R, et al. Randomised, double-blind, placebo-controlled treatment trial of fluoxetine and graded exercise for chronic fatigue syndrome. Br J Psychiatry 1998; 172: 485-490.
  • 9. Wallman KE, Morton AR, Goodman C, et al. Randomised controlled trial of graded exercise in chronic fatigue. Med J Aust 2004; 180: 444-448. <MJA full text>
  • 10. Ware JE, Sherbourne CD. The MOS 36-item Short-Form Health Survey (SF-36): conceptual framework and item selection. Med Care 1992; 6: 473-483.
  • 11. Royal Australasian College of Physicians Working Group. Chronic fatigue syndrome. Clinical practice guidelines — 2002. Med J Aust 2002; 176 (9 Suppl): S17-S55. <MJA full text>

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