The clinical utility of routine urinalysis in pregnancy

Deirdre J Murphy and Christopher W Redman
Med J Aust 2003; 178 (10): . || doi: 10.5694/j.1326-5377.2003.tb05336.x
Published online: 19 May 2003

To the Editor: Murray et al recently suggested that after an initial screening urinalysis, routine urinalysis could be eliminated from antenatal care without adverse outcomes for women.1 Their conclusions are based on a prospective observational study of 1000 women, 26 of whom developed pre-eclampsia, with 6/24 (25%) developing new proteinuria before the onset of hypertension. We have concerns about the authors' claims, which, we believe, are not justified by their findings.


  • 1. Murray N, Homer CSE, Davis GK, et al. The clinical utility of routine urinalysis in pregnancy: a prospective study. Med J Aust 2002; 177: 477-480. <eMJA full text>
  • 2. Brown MA, Hague WM, Higgins J, et al. The detection, investigation and management of hypertension in pregnancy: full consensus statement. Aust N Z J Obstet Gynaecol 2000; 40: 139-155.
  • 3. The Department of Health. Why mothers die: report on confidential inquiries into maternal deaths in the United Kingdom 1994-1996. London: HMSO, 1998.
  • 4. Murphy DJ, Stirrat GM. Mortality and morbidity associated with early onset pre-eclampsia. Hypertens Pregnancy 2000; 19: 221-231.
  • 5. Villar J, Carroli G, Khan-Neelofur D, et al. Patterns of routine antenatal care for low-risk pregnancy. Cochrane Database Syst Rev 2001; (4): CD000934.
  • 6. Villar J, Ba'aqeel H, Piaggio G, et al. WHO antenatal care randomised trial for the evaluation of a new model of routine antenatal care. Lancet 2001; 357: 1551-1564.


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