MJA 221 6 16 Sept cover

Issues

Volume 221 Issue 6

16 September 2024

Editor's choice

Health policy 16 September 2024 Free

Policy influential research: setting, informing and decoding our national health and social policy agenda and activities

The MJA aims to prioritise studies that will “advance knowledge or practice with respect to medical problems of significance for Australia”. This is particularly inclusive of studies that not only have the potential to affect clinical practice, but also to help set, inform and improve our national health and social policies. In this issue of the MJA, we showcase several studies that have and will continue to inform national policy, help us understand how evidence can be used to best effect in the health policy process, and remind us of how and what is being done about other important national policy priorities. Australia's journey in regulating vaping, a relatively recent yet significant public health threat, especially to younger people, has taken a positive turn this year. The Therapeutic Goods and Other Legislation Amendment (Vaping Reforms) Act 2024 took effect in July 2024 and significant more regulation to access, packaging, and formulations of vapes was introduced nationally (https://www.aph.gov.au/Parliamentary_Business/Bills_Legislation/bd/bd2324a/24bd061a). These changes are internationally recognised as bold attempts at curbing vaping among younger people and have been influenced by an enormous body of work and advocacy. It is work such as Jenkins and colleagues’ (https://doi.org/10.5694/mja2.52423) in this issue, which identified a synthetic nicotine analogue (6‐methylnicotine) in “non‐nicotine” vapes and accompanying inconsistent chemical reporting, that are the pillars of evidence required to inform our national legislative journey. As noted by Larcombe and Hunter (https://doi.org/10.5694/mja2.52422) in an accompanying editorial, loopholes in legislation will continue to be used by vape manufacturers and our regulatory bodies must keep up, or ideally get in front of their attempts at circumventing them using evidence like that presented by Jenkins and colleagues. This issue of the MJA also includes a compendium piece for readers of modelled economic evaluations by Chen and colleagues (https://doi.org/10.5694/mja2.52409). Economic evaluations are ubiquitous and critical to how Australia makes decisions about medicines, devices, and other health care services (https://www.sciencedirect.com/science/article/pii/S221210992030666X), yet not always clearly accessible to non‐health economist readers. Chen et al remind us that with more complex questions, interventions, heterogenous populations, and luckily more computational power, more sophisticated model‐based economic evaluations are required, unavoidable, and our understanding of them must evolve. Using two recent MJA studies as examples (https://doi.org/10.5694/mja2.51825, https://doi.org/10.5694/mja2.51860), Chen et al describe how model‐based evaluations compare to study‐based evaluation, major modelling choices with powerful visual representations of these models and advice on what to look out for when determining model robustness. In Engel and Mihalopoulos’ perspective (https://doi.org/10.5694/mja2.52414), we read about loneliness and its economic impact, an area of increasing national recognition and evolving health and social policies. Loneliness, affecting almost one‐third of adults over 60 years of age and two‐thirds of older adults living in residential care, needs cost‐effective national strategies. Although a bidirectional relationship between loneliness and chronic health problems is not surprising, the magnitude of its potential health effects (eg, 26% higher risk of death), and the increasingly obvious impact that it has on our health system ($2.7 billion annually) that Engel and Mihalopoulos cite is alarming. However, it is not all doom and gloom. Engel and Mihalopoulos suggest that research has identified some critical elements of successful loneliness intervention strategies, including holistic community‐based and ‐led health and social care, and several promising intervention types. Interestingly, one such proposed strategy to address loneliness is “social prescribing”, which Yadav and colleagues’ (https://doi.org/10.5694/mja2.52413) letter to the editor introduces as the “core business” of Aboriginal and Torres Strait Islander community‐controlled health organisations. Yadav et al's call to action that we should learn more from Indigenous models of social prescribing could not have come at a more pertinent time.

Maria Inacio

Perspective

Medical education

Erratum

19 July 2024 Free

Erratum

Chaturvedi S, Ullah S, Hughes (Wagadagam) JT. Kidney transplantation access and outcomes for Aboriginal and Torres Strait Islander children and young adults, 1963–2020: an ANZDATA registry study. Med J Aust 2024; https://doi.org/10.5694/mja2.52355 In the Results section of the Abstract, where it says “Five-and 10-year survival after kidney transplantation was similar for Aboriginal and Torres Strait Islander and non-Indigenous people”, it should read “Five-and 10-year patient survival after kidney transplantation was similar for Aboriginal and Torres Strait Islander and non-Indigenous people”. On page 48, the first sentence of the Methods section should start with “We used data prospectively …”. On page 48, in the Study outcomes section, where it says “Primary outcomes were time to first kidney transplantation, death, death-censored graft survival, and survival for people with end-stage kidney disease who did not receive kidney transplants (ie, remained on dialysis) during 1963–2020”, it should read “Primary outcomes were time to first kidney transplantation, death, death-censored graft survival, and survival for children and young adults with end-stage kidney disease who did not receive kidney transplants (ie, remained on dialysis) during 1963–2020”. On page 48, in the second paragraph of the Variables section, where it says “… cyclosporine/mycophenolate/ prednisone; 005–2020”, it should read “… cyclosporine/mycophenolate/ prednisone; 2005–2020”. On page 48, in the third paragraph of the Variables section, where it says “The status at modality treatment transition is defined as receiving a transplant, death, on dialysis, own kidney function recovered, or date of most recent visit if lost to follow-up”, it should read “The status at transition is defined as received transplant, patient death, on dialysis, own kidney function recovered, or date of most recent visit if lost to follow-up”.

Editorial

Research

Research letter

Narrative review

Letter to the editor

News

2 September 2024 Media release Free

There is a longstanding tradition in the medical world of naming diseases and conditions after individuals who made valuable contributions to their discovery.

There is a longstanding tradition in the medical world of naming diseases and conditions after individuals who made valuable contributions to their discovery. But who gets to be an eponym, who gets forgotten and should they be used at all? In a perspective published in the Medical Journal of Australia, Dr Leya Nedumannil and Dr Diana Lewis of Northern Hospital, Melbourne question the continued use of the naming style. “While not with the purpose to discredit the diligence of nor imply that unethical intentions always drove those after whom eponyms are coined, we believe their ongoing use in medicine without reflective deliberation may be detrimental,” the authors wrote. The academics say that in some cases the broader teams who were involved in medical discoveries don’t get the same recognition as the person with the eponym. An example of this is seen with Crohn’s disease, which is named after Burril B Crohn despite two other authors co-writing the paper where the condition was first described — Leon Ginzberg and Gordon D Oppenheimer. “Medical progress is seldom a solo feat, and the use of eponyms may threaten important values of collaboration and collegiality in this realm,” Dr Nedumannil and Dr Lewis wrote. Women throughout history have also been excluded with only 4% of medical eponyms being credited to women. “Numerous women have historically had their scientific achievements forgotten or inaccurately credited to men, a notion of systemic bias so widespread that it has ironically acquired an evocative eponymous title itself [the Matilda Effect], named after suffragist Matilda Gage,” the authors wrote. When names are best left in the past Another unintended consequence of using medical eponyms occurs when an individual is found to have engaged in unethical research or even crimes against humanity, as in the case of research undertaken by Nazi collaborators. “An example is the replacement of Wegener granulomatosis with granulomatosis with polyangiitis, due to Friedrich Wegener’s associations with the Nazi Party,” the authors wrote. There is also a risk of medical eponyms continuing a culture of colonialism through favouring Eurocentric researchers over knowledge from other nations and cultures. Research shows that 97% of medical eponyms celebrate European and North American physicians, despite 40% of pharmacological agents used in current practice originating from non-western medicine. “The failure to acknowledge accomplishments of cultural medical practices that often pre-dated and potentially inspired those of conventional medicine is not uncommon, and some eponyms may reflect this,” the authors wrote. A diagnosis by any other name… Even from a merely logistical standpoint, eponyms can cause confusion due to multiple systems or conditions being named after the same person, and because eponyms are not descriptive of the condition, this can make it difficult to communicate with patients. Both Dr Nedumannil and Dr Lewis argue that moving away from the use of medical eponyms would help medical terms avoid ethical pitfalls, while creating opportunities for more easily understandable terminology. “This could not only help dissociate medical terminology from the contentious milieu in which several eponyms came to existence, but potentially also facilitate more precise communication between clinicians and with patients,” they concluded. Read the perspective in the Medical Journal of Australia. The Medical Journal of Australia is a publication of the Australian Medical Association. The statements or opinions that are expressed in the MJA reflect the views of the authors and do not represent the official policy of the AMA or the MJA unless that is so stated. Media contacts: For all MJA enquiries, please contact news and online editor, Sally Block, at mja-media@mja.com.au

Sally Block

Next Issue Volume 221 Issue 7

View more
MJA 221 7 7 Oct cover
Editor's choice 7 October 2024 Free

Theme issue on women's health: taking a holistic view

Francis Geronimo

Perspective 7 October 2024 Open Access

Pregnancy, childbirth and the postpartum period: opportunities to improve lifetime outcomes for women with non‐communicable diseases

Jenny A Ramson · Myfanwy J Williams · Bosede B Afolabi · Stephen Colagiuri · Kenneth W Finlayson · Bianca Hemmingsen · Kartik K Venkatesh · Doris Chou

Perspective 16 September 2024 Open Access

Leave no‐one behind: reducing health disparities for women experiencing homelessness in Australia

Lisa J Wood · Rhiannon C Villiers

Perspective 9 September 2024 Open Access

Pharmaceuticals in pregnancy: a multifaceted challenge in Australia

Stefan C Kane · Renuka Shanmugalingam · Amanda Henry

Previous Issue Volume 221 Issue 5

View more
MJA 221 5 2 Sept cover
Editor's choice 2 September 2024 Free

Building and acting on the evidence for primary prevention of cancer

Elizabeth Zuccala

Perspective 12 August 2024 Open Access

Overcoming disparities in hepatocellular carcinoma outcomes in First Nations Australians: a strategic plan for action

Jessica Howell · Troy Combo · Paula Binks · Kylie Bragg · Sarah Bukulatjpi · Kirsty Campbell · Paul J Clark · Melissa Carroll · Jane Davies · Teresa de Santis · Kate R Muller · Bella Nguyen · John K Olynyk · Nicholas Shackel · Patricia C Valery · Alan J Wigg · Jacob George · Stuart K Roberts

Perspective 19 August 2024 Open Access

Priorities for planetary health equity in Australia

Sharon Friel · Katherine Trebeck · Nicholas Frank · Sandro Demaio · Megan Arthur · Chelsea Hunnisett · Francis Nona

Perspective 2 September 2024 Open Access

Using conversant artificial intelligence to improve diagnostic reasoning: ready for prime time?

Ian A Scott · Tim Miller · Carmel Crock

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