Routine screening for vitamin D deficiency in early pregnancy: past its due date?

Peter R Ebeling
Med J Aust 2011; 194 (7): . || doi: 10.5694/j.1326-5377.2011.tb02999.x
Published online: 4 April 2011

Screening plus equitable provision of vitamin D supplements could mitigate many adverse outcomes

For nothing worthy proving can be proven,

  • NorthWest Academic Centre, University of Melbourne, Melbourne, VIC.


Competing interests:

I have received two research grants, one from sanofi-aventis, who market cholecalciferol in Australia, and one from DiaSorin in the US, who manufacture an assay for measurement of serum 25(OH)D. In addition, I am speaking at meetings for sanofi-aventis and DiaSorin later this year.

  • 1. Lau S, Gunton JE, Athayde NP, et al. Serum 25-hydoxyvitamin D and glycated haemoglobin in women with gestational diabetes mellitus. Med J Aust 2011; 194: 334-337. <MJA full text>
  • 2. Scragg R, Sowers M, Bell C. Serum 25-hydroxyvitamin D, diabetes, and ethnicity in the Third National Health and Nutrition Examination Survey. Diabetes Care 2004; 27: 2813-2818.
  • 3. Chiu KC, Chu A, Go VL, Saad MF. Hypovitaminosis D is associated with insulin resistance and beta cell dysfunction. Am J Clin Nutr 2004; 79: 820-825.
  • 4. Baynes KC, Boucher BJ, Feskens EJ, Kromhout D. Vitamin D, glucose tolerance and insulinaemia in elderly men. Diabetologia 1997; 40: 344-347.
  • 5. Forouhi NG, Luan J, Cooper A, et al. Baseline serum 25-hydroxy vitamin D is predictive of future glycemic status and insulin resistance: the Medical Research Council Ely Prospective Study 1990-2000. Diabetes 2008; 57: 2619-2625.
  • 6. Mattila C, Knekt P, Mannisto S, et al. Serum 25-hydroxyvitamin D concentration and subsequent risk of type 2 diabetes. Diabetes Care 2007; 30: 2569-2570.
  • 7. Bodnar LM, Simhan HN, Powers RW, et al. High prevalence of vitamin D insufficiency in black and white pregnant women residing in the northern United States and their neonates. J Nutr 2007; 137: 447-452.
  • 8. Teale GR, Cunningham CE. Vitamin D deficiency is common among pregnant women in rural Victoria. Aust N Z J Obstet Gynaecol 2010; 50: 259-261.
  • 9. Ebeling PR, Eisman JA. Vitamin D and osteoporosis. In: Feldman D, Pyke JW, Adams JS, editors. Vitamin D, Volume II. 3rd ed. Oxford, United Kingdom: Elsevier and Academic Press, 2011: 1129-1144.
  • 10. Ross AC, Manson JE, Abrams SA, et al. The 2011 report on dietary reference intakes for calcium and vitamin D from the Institute of Medicine: what clinicians need to know. J Clin Endocrinol Metab 2011; 96: 53-58.
  • 11. Mahon P, Harvey N, Crozier S, et al; SWS Study Group. Low maternal vitamin D status and fetal bone development: cohort study. J Bone Miner Res 2010; 25: 14-19.
  • 12. Javaid MK, Crozier SR, Harvey NC, et al; Princess Anne Hospital Study Group. Maternal vitamin D status during pregnancy and childhood bone mass at age 9 years: a longitudinal study. Lancet 2006; 367: 36-43.
  • 13. Hewison M, Adams JS. Vitamin D insufficiency and skeletal development in utero. J Bone Miner Res 2010; 25: 11-13.
  • 14. Camargo CA Jr, Ingham T, Wickens K, et al; the New Zealand Asthma and Allergy Cohort Study Group. Cord-blood 25-hydroxyvitamin D levels and risk of respiratory infection, wheezing, and asthma. Pediatrics 2011; 127: e180-e187.
  • 15. Healthy Start [website]. (accessed Mar 2011).


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