To the Editor: The revised recommendations for the use of the estimated glomerular filration rate (eGFR) in the clinical setting use the Modification of Diet in Renal Disease (MDRD) formula to adjust drug dosing in people with renal impairment (Recommendation 6).1 Although the utility of the MDRD-based eGFR as a screening tool to identify people with chronic kidney disease represents an important clinical opportunity, we, and others,2,3 remain concerned about this recommendation.
The full article is accessible to AMA members and paid subscribers. Login to read more or purchase a subscription now.
Please note: institutional and Research4Life access to the MJA is now provided through Wiley Online Library.
- 1. Mathew TH, Johnson DW, Jones GRD, on behalf of the Australasian Creatinine Consensus Working Group. Chronic kidney disease and automatic reporting of estimated glomerular filtration rate: revised recommendations. Med J Aust 2007; 187: 459-463. <MJA full text>
- 2. Roberts GW. Dosing of key renally cleared drugs in the elderly — time to be wary of the eGFR. J Pharm Prac Res 2006; 36: 204-209.
- 3. Faull R. Prescribing in renal disease. Aust Prescr 2007; 30: 17-20.
- 4. Prescribing in renal impairment. In: Australian medicines handbook. Adelaide: AMH, 2008: xiv-xv.