Combined treatment with angiotensin-converting enzyme inhibitors and angiotensin-receptor blockers to prevent end-stage kidney disease in patients who do not have diabetes

Giovanni FM Strippoli and Craig C Jonathan
Med J Aust 2004; 181 (8): . || doi: 10.5694/j.1326-5377.2004.tb06375.x
Published online: 18 October 2004

In patients without diabetes, but with impaired renal function and proteinuria, does combination treatment with the angiotensin-converting enzyme (ACE) inhibitor trandolapril and the angiotensin-receptor blocker (ARB) losartan prevent deterioration of renal function more effectively than treatment with either agent used alone?

  • Giovanni FM Strippoli1
  • Craig C Jonathan2

  • 1 Centre for Kidney Research, Cochrane Renal Group, NHMRC Centre of Clinical Research Excellence in Renal Medicine, The Children’s Hospital at Westmead, University of Sydney, Sydney, NSW.
  • 2 Centre for Kidney Research, NHMRC Centre of Clinical Research Excellence in Renal Medicine, Cochrane Renal Group, School of Public Health, University of Sydney, Australia, Sydney, NSW.


Competing interests:

None identified.


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