Volume 180 - Issue 8
Parallel infusion of hydrocortisone ± chlorpheniramine bolus injection to prevent acute adverse reactions to antivenom for snakebites
Authors: S Abeysingha M Kularatne and Indika B Gawarammana
Med J Aust 2004; 180 (8): 428. || doi: 10.5694/j.1326-5377.2004.tb06004.x
Published online: 19 April 2004
Published online: 19 April 2004
Re: “Parallel infusion of hydrocortisone ± chlorpheniramine bolus injection to prevent acute adverse reactions to antivenom for snakebites”, by Gawarammana I B, et al in the 5 January issue of the Journal (Med J Aust 2004; 180: 20-23). As a result of a programming error, the confidence intervals in Box 3 of the article were incorrect. Box 3 should be as follows.
3: Reactions to antivenom and time from antivenom infusion to reaction
Reaction |
Treatment A (n = 10) |
Treatment B (n = 21) |
Treatment C (n = 16) |
||||||||||
Mean |
Patients |
Mean |
Patients |
Mean |
Patients |
||||||||
No. |
% |
(95% CI) |
No. |
% |
(95% CI) |
No. |
% |
(95% CI) |
|||||
Hypotension (< 120/80 mmHg) |
43 |
5 |
33% |
(15%–58%) |
26 |
8 |
38% |
(21%–59%) |
22 |
9 |
56% |
(33%–77%) |
|
Tachycardia (> 80/min) |
42 |
5 |
33% |
(15%–58%) |
18 |
7 |
33% |
(17%–55%) |
16 |
10 |
63% |
(39%–82%) |
|
Rigors |
90 |
1 |
7% |
(1%–30%) |
38 |
6 |
29% |
(14%–50%) |
16 |
3 |
19% |
(7%–43%) |
|
Itching |
25 |
10 |
67% |
(42%–85%) |
16 |
10 |
48% |
(28%–68%) |
13 |
10 |
63% |
(39%–82%) |
|
Urticaria |
32 |
10 |
67% |
(42%–85%) |
19 |
8 |
38% |
(21%–59%) |
15 |
12 |
75% |
(51%–90%) |
|
Dyspnoea |
15 |
2 |
13% |
(4%–38%) |
— |
0 |
— |
— |
16 |
5 |
31% |
(14%–56%) |
|
Treatments: A, hydrocortisone and placebo; B, hydrocortisone and chlorpheniramine; C, placebo and placebo. |
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The html and pdf versions of the article appearing in the eMJA were corrected on 19 April 2004.