Cholestasis associated with the use of pravastatin sodium

Robert G Batey and Michelle Harvey
Med J Aust 2002; 176 (11): . || doi: 10.5694/j.1326-5377.2002.tb04559.x
Published online: 3 June 2002

To the Editor: Hydroxymethylglutaryl coenzyme-A (HMG Co-A) reductase inhibitors (or statins) are widely prescribed, and any class-specific side effect has the potential to affect many thousands of patients. The statin drugs are well recognised as a cause of mild and usually transient hepatitis.1-3 Cholestatic liver injury has been reported with simvastatin4 and atorvastatin,5 but pravastatin has only been implicated as a cause in one report.6

  • Robert G Batey
  • Michelle Harvey


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