Vitamin B12 supplementation futile for preventing demyelination in ongoing nitrous oxide misuse

Christopher Blair, Chris Tremonti, Leon Edwards, Paul S Haber and G Michael Halmagyi
Med J Aust 2019; 211 (9): . || doi: 10.5694/mja2.50371
Published online: 4 November 2019

To the Editor: Recreational misuse of nitrous oxide remains a significant public health problem,1 sustained in part by the ready availability online of gas‐containing canisters intended for use in the catering industry. Known as “nangs” or “whippits” and usually purchased in bulk, each canister contains 8 g of nitrous oxide. When inhaled, this gives a seconds‐long “high”, which is typically prolonged by using several “nangs” in a single session. Some individuals can consume hundreds each day.

  • Christopher Blair1,2
  • Chris Tremonti2
  • Leon Edwards1,2
  • Paul S Haber3
  • G Michael Halmagyi2

  • 1 Liverpool Hospital, Sydney, NSW
  • 2 Institute of Neuroscience, Royal Prince Alfred Hospital, Sydney, NSW
  • 3 Royal Prince Alfred Hospital, Sydney, NSW

Competing interests:

No relevant disclosures.


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