Reversible pancytopenia caused by severe copper deficiency in a patient with Wilson disease

Muhajir Mohamed, Anna Johnston, Andrew Maclaine Cross and Archna Sharma
Med J Aust 2018; 209 (1): . || doi: 10.5694/mja17.00831
Published online: 2 July 2018

Clinical record

  • 1 Launceston General Hospital, Launceston, TAS
  • 2 University of Tasmania, Launceston, TAS
  • 3 Royal Hobart Hospital, Hobart, TAS

Competing interests:

No relevant disclosures.

  • 1. Halfdanarson TR, Kumar N, Li CY, et al. Hematological manifestations of copper deficiency: a retrospective review. Eur J Haematol 2008; 80: 523-531.
  • 2. Cortese A, Zangaglia R, Lozza A, et al. Copper deficiency in Wilson’s disease: peripheral neuropathy and myelodysplastic syndrome complicating zinc treatment. Mov Disord 2011; 26: 1361-1362.
  • 3. Ala A, Walker AP, Ashkan K, et al. Wilson’s disease. Lancet 2007; 369: 397-408.
  • 4. Hoogenraad TU. Paradigm shift in treatment of Wilson’s disease: zinc therapy now treatment of choice. Brain Dev 2006; 28: 141-146.
  • 5. Gabreyes AA, Abbasi HN, Forbes KP, et al. Hypocupremia associated cytopenia and myelopathy: a national retrospective review. Eur J Haematol 2013; 90: 1-9.


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