Issues
Volume 203 Issue 2
Editorials
Non-invasive prenatal testing: the new era in reproductive medicine
Important advances in screening for genetic abnormalities have major ethical implications
Jan E Dickinson MD, FRANZCOG, DDU · Caroline M de Costa PhD, MPH, FRANZCOG
The spectacular recent trials of urgent neurointervention for acute stroke: fuel for a revolution
How should we redesign our stroke services in light of neurointerventional advances?
Richard I Lindley MD, FRCP(Edin), FRACP · Christopher R Levi BMedSci, MB BS, FRACP
News
Recruitment into clinical trials — patient, recruit thyself
A new Australian website allows potential clinical trial participants to find and register for trials themselves
Gordon McGurk PhD
Perspectives
Fostering creativity and innovation in the health system: the role of doctors-in-training in biomedical innovation and entrepreneurship
Doctors-in-training are well positioned to continue Australia’s strong history of biomedical innovation and entrepreneurship
Harris A Eyre MB BS(Hons) · Timothy Lindsay MB BS, MPhil, PGDipSurgAnat · James A Churchill MB BS, BMedSc · Oliver Cronin MB BS(Hons) · Arlen Meyers MD, MBA
Suppression clauses in university health research: case study of an Australian government contract negotiation
Have universities forgotten their role in promoting open enquiry?
Kypros Kypri PhD
State-based legal requirements for Schedule 8 prescriptions: why so complicated?
Inconsistent Schedule 8 prescription requirements between Australian states and territories create unnecessary complexity for health professionals
Andy C Hua BPharm · Finna Shen BPharm · Xiaoting Ge RN, CCRN
Letters
Knowledge of non-invasive prenatal testing among pregnant women
A brief survey highlights the high level of NIPT awareness among pregnant women
Susannah J Maxwell MPH, BSc · Jan E Dickinson MD, FRANZCOG, DDU · Peter O’Leary PhD, MAACB, FFSc(RCPA)
Toxic epidermal necrolysis — an investigation to dye for?
Toxic epidermal necrolysis associated with use of contrast medium (comment on case report)
Lloyd J Ridley MB BS, FRANZCR · Sandhya Limaye PhD, FRACP, FRCPA
Hereditary leiomyomatosis and renal cell carcinoma syndrome
A rare benign carcinoma is caused by a mutation in the fumarate hydratase gene
Nira Chinniah MB BS(Hons), MMed(Clin Epi) · Patricia Lowe MB BS(Hons), MMed, FACD
Heatwave and risk of heat-related burn injury in children in Western Australia
Heatwave conditions correlate with increased heat exhaustion, sunburn and contact burns in kids
Lisa Martin RN, MPubHealth · Sally A Burrows BMath, GradDipMedStat · Fiona M Wood FRACS
Eight challenges faced by general practitioners caring for patients after an acute coronary syndrome
Counselling and pharmacotherapy are more effective than unassisted cessation of smoking
Colin P Mendelsohn MB BS(Hons) · Paul V Camp MN, GradDipHealthPromotion, CertSmokingCessation
Eight challenges faced by general practitioners caring for patients after an acute coronary syndrome
Many smokers quit on their own, and unassisted quitting should be considered before other methods
Peter L Thompson MD, FRACP, FACC · Alistair W Vickery MB BS, FRACGP
Clinical focus
General practice after-hours incentive funding: a rationale for change
The PIP after-hours incentive funding mechanism does not preferentially support practices that provide after-hours care
Amanda L Neil BSc(Hons), GradDipEc, PhD · Mark R Nelson MB BS(Hons), PhD, FRACGP · Tracy Richardson BBus, GradDipHlthHumServ · Meghan Mann-Leonard BSpThy · Andrew J Palmer BMedSc, MB BS
Update on the diagnosis and management of gout
Existing therapies and recent developments in the management of a common clinical problem
Kimberley Ting MB BS · Scott W Graf MB BS(Hons), FRACP · Samuel L Whittle MB BS(Hons), MClinEpid, FRACP
Guidance concerning the use of glycated haemoglobin (HbA1c) for the diagnosis of diabetes mellitus
Glycated haemoglobin assessment may be an efficient and simple tool for early diagnosis of diabetes mellitus
Michael C d’Emden MB BS, PhD, FRACP · Jonathan E Shaw MD, FRACP, FRCP(UK) · Graham R Jones MB BS, DPhil, FRCPA · N Wah Cheung MB BS, PhD, FRACP
Research
Geographical mobility of general practitioners in rural Australia
Understanding push and pull factors helps in targeting medical workforce maldistribution in rural and remote areas
Matthew R McGrail BSc(Hons), GradDipIT, PhD · John S Humphreys BA, DipEd, PhD
Australian clinical trial activity and burden of disease: an analysis of registered trials in National Health Priority Areas
Some high-burden areas of disease fall short in research efforts
Jacquelyne Lam MPharm, BSc · Sarah J Lord MB BS, MS, FRACGP · Kylie E Hunter BA(Human Movement)(Hons), BA(Indonesian) · R John Simes MB BS(Hons), MD, FRACP · Thuyen Vu BSc · Lisa M Askie PhD, MPH, BN
Readmissions after stroke: linked data from the Australian Stroke Clinical Registry and hospital databases
Linked data show that readmission to hospital is common for patients with stroke or TIA
Monique F Kilkenny MPH, GDipEpiBiostats, BAppSc(MRA) · Helen M Dewey MB BS, PhD, FRACP · Vijaya Sundararajan BA(Hons), MD, MPH · Nadine E Andrew PhD, MPH, BAppSc(Physio) · Natasha Lannin PhD, GradDip(CaseMgmt), BSc(OT) · Craig S Anderson MB BS, PhD, FRACP · Geoffrey A Donnan MB BS, MD, FRACP · Dominique A Cadilhac PhD, MPH, BN
Case reports
Febuxostat-associated rhabdomyolysis in chronic renal failure
Statin therapy in patients with chronic kidney disease can be risky
Debasish Ghosh MB BS · Philippa M McGann BPharm · Timothy J Furlong PhD, FRACP · Richard O Day MD, FRACP
Spinal gout mimicking osteomyelitis
Gout can affect the spine, looking suspiciously like osteomyelitis
Minnie Au MB BS · John Wood MB BS(Hons)
Ethics and law
Records access and management on closure of a medical practice
Health practitioners who close a practice have immediate and ongoing legal obligations to their patients
David J Carter LLM(Res), LLB(Hons), BAComm
Reflections
Medicine in a Roman city
The excavated city of Pompeii provides insight into medicine in first century CE Roman life
Peter R Mayall MA, FRCOG, FRANZCOG
A French naval surgeon's account of disease, treatments and hospitals in colonial Sydney, 1873
Early Australian environmental, social and public health conditions observed by a French “man of science”
Simon Barraclough BA(Hons), MA, PhD · Arnaud Gallois BA(Hons), DipEd
Ronald Lawrie Huckstep CMG, MD, FRCS, FRACS
Ron Huckstep was known around the world for his work in orthopaedics, trauma and polio
Jeremy Chapman MD, FRACP, FRCP
The Sick Room
Here he is, entering though still, a painting hung in the doorway
Heather Taylor Johnson
Careers
Learning for life
Dr Frank Jones, president of the Royal Australian College of General Practitioners, is passionate about the front-and-centre role GPs have played and will continue to play in the long-term health of Australians.
Cate Swannell
Around the universities
Professor Rodney Phillips, an immunologist specialising in HIV and infectious disease whose distinguished career encompasses clinical practice, research and a number of influential medical administrative roles at Oxford University, has been appointed as Dean of the School of Medicine at the University of New South Wales. An Australian who lived in the United Kingdom for 35 years, Professor Phillips graduated from the University of Melbourne and began his career at the Royal Melbourne Hospital. During this time he served for 6 months as medical registrar in Rabaul, Papua New Guinea, where his encounters with tropical diseases such as endemic malaria, tuberculosis and leprosy sparked a lifelong research interest in the substantial health problems of resource-poor countries. He moved to Guy’s Hospital in London in 1981 and joined Oxford University as a research lecturer in 1983, which allowed him to spend 4 years conducting bedside research in Thailand, Burma and Sri Lanka on patients with severe malaria, rabies and snakebite. Back in the United Kingdom in 1986, he embarked on the retroviral research for which he is best known. His initial research interest was genetic variation in HTLV-1, the first human retrovirus to be isolated, and he then went on to study the immunology of HIV. His Oxford research group described for the first time how HIV evades cytotoxic T cells, and this basic research has led to much greater understanding of the challenges posed by the massive adaptive capacity of HIV. Professor Phillips’s current research aims to understand the interaction between persistent viruses, particularly HIV/AIDS, and humans. As well as basic research, he collaborates widely on clinical trials and has spent many years conducting clinical research into HIV in the KwaZulu-Natal province and Bloemfontein in South Africa. During his 34 years at Oxford University, Professor Phillips served as Professor of Medicine and went on to become Head of Research and Associate Dean of the Division of Medical Sciences. He took up the position as Vice-Dean of Medical Sciences in 2011. He served as Director of the Peter Medawar Building for Pathogen Research, a research institute of about 150 investigators studying complex pathogens and the genetics of their human hosts, and was Co-Director of the Oxford Martin Institute for Emerging Infections, a unit aimed at investigating pandemic viral infections. He is a Fellow of the Royal Australasian College of Physicians, the Royal College of Physicians (London), the Academy of Medical Sciences, and an Honorary Fellow of Oxford’s Pembroke College. Source: http://med.unsw.edu.au/dean Professor David Craik, from the University of Queensland’s Institute for Molecular Bioscience, has been awarded a $2.97 million Australian Laureate Fellowship for his work with cyclic peptides. His program as an Australian Research Council Laureate will aim to find a way to turn peptides, produced naturally in plants, into stable, protein-based drugs that can be taken in the form of an edible plant seed (bio-pill) and used to treat a range of diseases with fewer side effects than existing therapies. “This funding will help support talented young researchers in my group to translate their work into tangible outcomes”, Professor Craik said. “Peptides (mini proteins) are creating much excitement in the pharmaceutical industry, and the work funded in this fellowship will help to realise their potential as ‘next generation’ medicines.” Source: https://www.uq.edu.au/news/article/2015/06/uq-leads-nation-prestigious-arc-laureate-fellowships Sleep disorder expert Professor Peter Cistulli has been appointed the ResMed Chair in Sleep Medicine at the University of Sydney. Professor Cistulli will lead the University’s research, clinical and educational activities in advancing the field of sleep-disordered breathing and its impact on chronic disease management. The new Chair is funded by ResMed and will work across the University’s Faculty of Medicine and Charles Perkins Centre. “As the ResMed Chair I will pursue my overarching vision for sleep to be recognized as a vital physiological function for wellbeing and health, with a focus on the role of sleep-disordered breathing and its impact on many chronic diseases”, Professor Cistulli said. “We have a huge opportunity to better co-ordinate research and education activities across our University to deliver real life solutions for the many sufferers of sleep disorders, as well as training our next generation of researchers and clinicians in the field.” Professor Cistulli has been an active researcher clinician in respiratory and sleep medicine for 25 years, and has worked at the University as Professor of Respiratory Medicine for the past 10 years. He heads the Centre for Sleep Health and Research at Sydney’s Royal North Shore Hospital. Source: http://sydney.edu.au/news/84.html?newsstoryid=15165
Cate Swannell
Changing roles
Charles Guest MPH, PhD, FAFPHM
Appropriate use of oxygen in acute medicine
E Walters FRCP, FRACP, DM · Greg King PhD, FRACP
News briefs
Cate Swannell
Making sense of alcohol consumption data in Australia
Farhat Yusuf BSc(Hons), MA, PhD · Stephen R Leeder MD, PhD, FRACP
Celebrating 10 years of collaboration: the Australian Indigenous Doctors' Association and Medical Deans Australia and New Zealand
Tammy Kimpton BMed, FRACGP · Peter J Smith MD, FRACP, FRCPA
Time to move to a glycated haemoglobin-based algorithm for diabetes screening and diagnosis?
Stephen Colagiuri MB BS, FRACP