In reply: I thank Griffin and Kelly for elaborating on some practical elements of immigration screening for latent tuberculosis infection (LTBI) in light of their experience with isoniazid prophylactic therapy in a high-risk context.
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- 1. McBryde E, Denholm JT. Risk of active tuberculosis in immigrants: effects of age, region of origin and time since arrival in a low-exposure setting. Med J Aust 2012; 197: 458-461.
- 2. Diel R, Loddenkemper R, Niemann S, et al. Negative and positive predictive value of a whole-blood interferon- release assay for developing active tuberculosis: an update. Am J Respir Crit Care Med 2011; 183: 88-95.
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