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Tramadol and new-onset seizures

Angelo Labate, Mark R Newton, Graeme M Vernon and Samuel F Berkovic
Med J Aust 2005; 182 (1): 42-43.

Angelo Labate,* Mark R Newton,† Graeme M Vernon,‡ Samuel F Berkovic§

* Research Fellow, Brain Research Institute, † Neurologist, § Director, Epilepsy Research Centre, ‡ Drug Information Pharmacist, Austin Health, Heidelberg West, VIC 3081. s.berkovicATunimelb.edu.au

Angelo Labate, Research Fellow2
Mark R Newton, Neurologist2
Graeme M Vernon, Director3
Samuel F Berkovic, Drug Information Pharmacist3
1 Brain Research Institute
3 Epilepsy Research Centre
4 Austin Health, Heidelberg West, VIC 3081. s.berkovicATunimelb.edu.au
Article References: 
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Kahn LH, Alderfer RJ, Graham DJ. Seizures reported with tramadol. JAMA 1997; 278: 1661.
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9388083
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Gasse C, Derby L, Vasilakis-Scaramozza C, Jick H. Incidence of first-time idiopathic seizures in users of tramadol. Pharmacotherapy 2000; 20: 629-634.
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Gardner JS, Blough D, Drinkard CR, et al. Tramadol and seizures: a surveillance study in a managed care population. Pharmacotherapy 2000; 20: 1423-1431.
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11130214
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Jick H, Derby LE, Vasilakis C, Fife D. The risk of seizures associated with tramadol. Pharmacotherapy 1998; 18: 607-611.
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9620111
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i1085825
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King MA, Newton MR, Jackson GD, et al. Epileptology of the first-seizure presentation: a clinical, electroencephalographic, and magnetic resonance imaging study of 300 consecutive patients. Lancet 1998; 352: 1007-1011.
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Australian Government. Health Insurance Commission. Available at: www.hic.gov.au/statistics/dyn_pbs/forms/pbs_tab1.shtml (accessed Nov 2004).
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Reference Link: 
i1085829

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