Heart failure: how can we prevent the epidemic?
Authors: Matthew T Naughton, Darren R Mansfield, David M Kaye, Peter Bergin and Meroula Richardson
Published online: 2 February 2004
Matthew T Naughton,* Darren R Mansfield,* David M Kaye,† Peter Bergin,† Meroula Richardson†
* Respiratory Physician, † Cardiologist, Alfred Hospital, PO Box 315, Prahran, VIC 3181. m.naughtonATalfred.org.au
To the Editor: We were surprised that Campbell’s recent article on heart failure1 made no mention of sleep apnoea. This is despite the fact that about 50% of heart failure patients have sleep apnoea (either central or obstructive) and that quite a large body of literature now supports a causative relationship between obstructive sleep apnoea and congestive heart failure, supported by recent authoritative reviews. 2-4 Canine studies have shown that, in the absence of any other variable, obstructive sleep apnoea results in left ventricular systolic and diastolic dysfunction.
Importantly, the impact of continuous positive airway pressure (CPAP) in acute cardiogenic pulmonary oedema and subacute pulmonary oedema (central sleep apnoea) and heart failure in the setting of obstructive sleep apnoea are not mentioned. Identification and treatment of sleep apnoea in people with heart failure is supported by a trial we have recently conducted in which significant improvements in quality of life and objective markers of cardiac function were seen in patients treated with nasal CPAP.5
References
- Campbell DJ. Heart failure: how can we prevent the epidemic? Med J Aust 2003; 179: 422-425. <eMJA full text>
- Bradley TD, Floras JS. Sleep apnea and heart failure. Part I: obstructive sleep apnea. Circulation 2003; 107: 1671-1678. i1082887
- Bradley TD, Floras JS. Sleep apnea and heart failure. Part II: central sleep apnea. Circulation 2003; 107: 1822-1826.
- Jessup M, Brozena S. Heart failure. N Engl J Med 2003; 348: 2007-2018. CBBFCFAG
- Mansfield DR, Gollogly NC, Kaye DM, et al. A randomised controlled trial of continuous positive airway pressure treatment of obstructive sleep apnoea and heart failure. Am J Respir Crit Care Med. In press. CBBBGHBH