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Is subcutaneous or intramuscular naloxone as effective as intravenous naloxone in the treatment of life-threatening heroin overdose?

Jason Wasiak and Ornella Clavisi
Med J Aust 2002; 176 (10): 495.
Published online: 20 May 2002

"Is subcutaneous (SC) or intramuscular (IM) naloxone as effective as intravenous (IV) naloxone in the treatment of life-threatening heroin overdose?" An emergency department clinician was interested in comparing routes of administration of naloxone in light of anecdotal evidence suggesting that various routes may not be equally efficacious in restoring a patient to spontaneous breathing and consciousness.

  • Jason Wasiak1
  • Ornella Clavisi2

  • Centre for Clinical Effectiveness, Monash Institute of Health Services Research, Clayton, VIC.

Correspondence: cce@med.monash.edu.au

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