"Is subcutaneous (SC) or intramuscular (IM) naloxone as effective as intravenous (IV) naloxone in the treatment of life-threatening heroin overdose?" An emergency department clinician was interested in comparing routes of administration of naloxone in light of anecdotal evidence suggesting that various routes may not be equally efficacious in restoring a patient to spontaneous breathing and consciousness.
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- Centre for Clinical Effectiveness, Monash Institute of Health Services Research, Clayton, VIC.
Correspondence: cce@med.monash.edu.au
- 1. Wagner K, Brough L, MacMillan I, et al. Intravenous vs subcutaneous naloxone for out of hospital management of presumed opioid overdose. Acad Emerg Med 1998; 5: 293-299.
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