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Adverse effects of adult topical androgen use on children

Jacqueline K Hewitt and Margaret R Zacharin
Med J Aust 2012; 197 (9): . || doi: 10.5694/mja12.11042
Published online: 5 November 2012

To the Editor: We read with interest the report by Handelsman describing an increase in Australian testosterone prescriptions, including a particular increase in prescribing of topical testosterone gel.1


  • Royal Children’s Hospital, Melbourne, VIC.


Correspondence: jacky.hewitt@rch.org.au

Competing interests:

No relevant disclosures.

  • 1. Handelsman DJ. Pharmacoepidemiology of testosterone prescribing in Australia, 1992–2010. Med J Aust 2012; 196: 642-645. <MJA full text>
  • 2. Patel A, Rivkees SA. Prenatal virilization associated with paternal testosterone gel therapy. Int J Pediatr Endocrinol 2010; 2010: 867471.
  • 3. Kunz GJ, Klein KO, Clemons RD, et al. Virilization of young children after topical androgen use by their parents. Pediatrics 2004; 114: 282-284.
  • 4. Voelker R. Children’s exposure to testosterone gel spurs FDA to order boxed label warning. JAMA 2009; 301: 2428.

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