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Stop taking warfarin? No way!

James A Fink
Med J Aust 2009; 191 (10): . || doi: 10.5694/j.1326-5377.2009.tb03324.x
Published online: 16 November 2009

To the Editor: I appreciated Brukner’s perspective on treatment of venous thromboembolism (VTE),1 but I do feel some additional considerations and clarifications are in order.


  • Gold Coast Hospital — Robina, Robina, QLD.



  • 1. Brukner PD. Stop taking warfarin? No way! Med J Aust 2009; 190: 704. <MJA full text>
  • 2. Kearon C. Stopping anticoagulant therapy after an unprovoked venous thromboembolism. CMAJ 2008; 179: 401-402.
  • 3. Kearon C, Kahn SR, Agnelli G, et al. Antithrombotic therapy for venous thromboembolic disease: American College of Chest Physicians evidence-based clinical practice guidelines. Chest 2008; 133 (6 Suppl): 454S-545S.
  • 4. Rodger MA, Kahn SR, Wells PS, et al. Identifying unprovoked thromboembolism patients at low risk for recurrence who can discontinue anticoagulant therapy. CMAJ 2008; 179: 417-426.
  • 5. Palareti G, Cosmi B, Legnani C, et al. D-dimer testing to determine the duration of anticoagulation therapy. N Engl J Med 2006; 355: 1780-1789.
  • 6. Verhovsek M, Douketis JD, Yi Q, et al. Systematic review: D-dimer to predict recurrent disease after stopping anticoagulant therapy for unprovoked venous thromboembolism. Ann Intern Med 2008; 149: 481-490.
  • 7. Glynn RJ, Ridker PM, Goldhaber SZ, et al. Effects of random allocation to vitamin E supplementation on the occurrence of venous thromboembolism. Circulation 2007; 116: 1497-1503.
  • 8. National Health and Medical Research Council Clinical Trials Centre. Aspirin to prevent recurrent venous thromboembolism (ASPIRE). http://www.ctc.usyd.edu.au/trials/other_trials/aspire.htm (accessed Sep 2009).

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