A new model of depression with meaningful subtypes will avoid simplistic treatments
When you hear the term “major depression”, you imagine a clinically meaningful entity. Think “pseudoentity”, know “paradigm failure”.1 If I took my tegument for dermatological inspection, a diagnosis of “major” or “minor” blotches would be uninformative. I would need more categorical information (eg, freckle, melanoma) to make rational treatment choices. However, non-specificity now rules in depression modelling and treatment.
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- Black Dog Institute, Prince of Wales Hospital, Randwick, NSW.
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