Recreational nitrous oxide misuse is resulting in serious neurological impairment and persistent disability among users

Simon Mosalski, Anne Tanner and Christine T Shiner
Med J Aust 2021; 215 (5): . || doi: 10.5694/mja2.51201
Published online: 6 September 2021

To the Editor: Published evidence recognises that the recreational misuse of nitrous oxide (N2O) can be associated with vitamin B12 deficiency and subacute combined degeneration of the spinal cord.1 Misuse of N2O is increasing,2 with canisters (known as “nangs” or “whippits”) readily available for legal purchase in convenience stores and online ostensibly for the purpose of whipping cream.

  • 1 St Vincent’s Hospital Sydney, Sydney, NSW
  • 2 University of New South Wales, Sydney, NSW


Competing interests:

No relevant disclosures.


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