In reply: We wish to make some comments in response to Haines’s point that the PIVOT (Prostate Cancer Intervention Versus Observation Trial) failed to show any benefit from radical prostatectomy (RP) over surveillance.
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- 4. Carlsson S, Vickers AJ, Roobol M, et al. Prostate cancer screening: facts, statistics, and interpretation in response to the US Preventive Services Task Force Review. J Clin Oncol 2012; 30: 2581-2584.
- 5. Wolters T, Roobol MJ, Steyerberg EW, et al. The effect of study arm on prostate cancer treatment in the large screening trial ERSPC. Int J Cancer 2010; 126: 2387-2393.
- 6. Heijnsdijk EA, Wever EM, Auvinen A, et al. Quality-of-life effects of prostate-specific antigen screening. N Engl J Med 2012; 367: 595-605.
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