Improving recruitment to clinical trials for regional and rural cancer patients through a regionally based clinical trials network

Arun Muthusamy, Donna Long and Craig R Underhill
Med J Aust 2021; 214 (10): . || doi: 10.5694/mja2.51078
Published online: 7 June 2021

A new clinical trials network aims to bridge the gap in cancer outcomes between rural and metropolitan cancer patients in Victoria

In general, regional and rural patients have poorer cancer outcomes compared with their city counterparts.1 Although one‐third of the Australian population live in rural and regional areas, there is ongoing inequity in access to care among regional Australians.2 Over the decade to 2010, the disparity in cancer outcomes between rural and urban patients remained unchanged with 7% excess mortality (equating to about 9000 additional rural deaths).3,4 Until recently, clinical trials were almost exclusively conducted in metropolitan health institutions. Although a gateway to new treatments that can result in improved survival, clinical trials may be out of reach for many regional and rural cancer patients owing to distance.2,5,6,7,8,9,10 In 2016, the rate of cancer trial participation was 6.7% in metropolitan Melbourne, but only 1.2% in regional Victoria.4 In that year, a total of 443 patients from regional Victoria accessed clinical cancer trials, but 343 of those regional patients travelled to Melbourne to access a trial.4 We postulate that low rates of trial participation may be a contributing factor to lower cancer 5‐year survival in regional Victoria (66% compared with 70% in metropolitan Melbourne).4

  • Arun Muthusamy1
  • Donna Long2
  • Craig R Underhill1,3

  • 1 Border Medical Oncology, Albury, NSW
  • 2 Regional Trials Network Victoria, Albury, NSW
  • 3 Rural Clinical School, UNSW, Albury, NSW


The authors and the RTNV thank the Victorian Cancer Council and Victorian Cancer Agency for funding this project. The funding sources played no part in the planning, writing or publication of the work. We also acknowledge and thank colleagues from the RTNV sites, Cancer Trials Australia and others who contributed to this project, VCCC colleagues for collaboration on the teletrials component, and the patients and their carers who gave their consent to enrol in a clinical trial.

Competing interests:

Donna Long is employed under the grant from the funders acknowledged above.


remove_circle_outline Delete Author
add_circle_outline Add Author

Do you have any competing interests to declare? *

I/we agree to assign copyright to the Medical Journal of Australia and agree to the Conditions of publication *
I/we agree to the Terms of use of the Medical Journal of Australia *
Email me when people comment on this article

Online responses are no longer available. Please refer to our instructions for authors page for more information.