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Management of adverse events related to new cancer immunotherapy (immune checkpoint inhibitors)

Rose Liu, Pablo Fernandez-Peñas and Deshan F Sebaratnam
Med J Aust 2017; 206 (9) || doi: 10.5694/mja16.01357
Published online: 15 May 2017

The well researched narrative review by Bourke and colleagues1 offers a comprehensive overview of immune-related adverse events (irAEs) in cancer immunotherapy and their management. However, care needs to be taken in adopting too broad an approach, particularly in relation to dermatological irAEs.

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  • 1 Royal Prince Alfred Hospital, Sydney, NSW
  • 2 Westmead Hospital, Sydney, NSW
  • 3 University of Sydney, Sydney, NSW
  • 4 Skin and Cancer Foundation Australia, Sydney, NSW


Correspondence: d.sebaratnam@hotmail.com

Competing interests:

No relevant disclosures.

  • 1. Bourke JM, O’Sullivan M, Khattak MA. Management of adverse events related to new cancer immunotherapy (immune checkpoint inhibitors). Med J Aust 2016; 205: 418-424. <MJA full text>
  • 2. Hwang SJE, Anforth R, Carlos G, Fernandez-Penas P. Cutaneous adverse events of new anti-melanoma therapies: classification and management. Actas Dermosifiliogr 2017; 108: 6-16.
  • 3. Hwang SJ, Carlos G, Wakade D, et al. Cutaneous adverse events (AEs) of antiprogrammed cell-death (PD)-1 therapy in patients with metastatic melanoma: a single-institution cohort. J Am Acad Dermatol 2016; 74: 455-461.
  • 4. Carlos GRM, Fernandez-Penas P, Uribe P. Rational use of topical corticosteroids. Aust Prescr 2013; 36: 159-161.
  • 5. Sebaratnam DF, Murrell DF. Dermatology training and practice in Australia. Int J Dermatol 2014; 53: 1259-1264.

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