Connect
MJA
MJA

Comparative effectiveness research — the missing link in evidence-informed clinical medicine and health care policy making

Ian A Scott
Med J Aust 2013; 198 (6): 310-312. || doi: 10.5694/mja12.10504

To change practice, we should move beyond trial-based efficacy to real-world effectiveness

Meaningful health care reform requires robust evidence about which interventions work best for whom and under what circumstances. The Institute of Medicine in the United States has estimated that less than 50% of current treatments are supported by evidence and 30% of health care expenditure reflects care that is of uncertain value.1 In studies testing established clinical standards of care, more than half reported evidence that contradicts standard care or is inconclusive.2 Many Medicare Benefits Schedule services lack comprehensive evidence of comparative safety or effectiveness, while many that have been evaluated have been shown to be ineffective, harmful or of uncertain value compared with alternative forms of care.3

  • Ian A Scott

  • Department of Internal Medicine and Clinical Epidemiology, Princess Alexandra Hospital, Brisbane, QLD.


Competing interests:

No relevant disclosures.

Author

remove_circle_outline Delete Author
add_circle_outline Add Author

Comment
Do you have any competing interests to declare? *

I/we agree to assign copyright to the Medical Journal of Australia and agree to the Conditions of publication *
I/we agree to the Terms of use of the Medical Journal of Australia *
Email me when people comment on this article

Responses are now closed for this article.