Comparative effectiveness research — a proposal for a new NHMRC funding stream

John R Zalcberg
Med J Aust 2012; 196 (1): . || doi: 10.5694/mja11.10036
Published online: 16 January 2012

Opportunities to examine the relevance of health interventions in actual clinical scenarios need to be created

Evidence-based medicine underpins high-quality health care.1 The use of evidence in the practice of medicine informs appropriate decision making, reduces variability in clinical practice and helps ensure improvement of patient outcomes. Most evidence relating to new knowledge is derived from randomised clinical trials.2,3

  • John R Zalcberg

  • Division of Cancer Medicine, Peter MacCallum Cancer Centre and University of Melbourne, Melbourne, VIC.


Competing interests:

I completed a 3-month sabbatical at the National Institute of Clinical Studies in 2009, was the recipient of multiple NHMRC project grants, and have served on various NHMRC committees. I am also Chair of the Australasian Gastro-Intestinal Trials Group, under whose auspices several of the trials mentioned or alluded to in this article have occurred.


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