An estimated four out of five Australians with coeliac disease are undiagnosed — we need greater awareness and increased testing
According to criteria published in 1990, which remain the most widely accepted, the diagnosis of coeliac disease is based on typical histological features of the small intestine of an individual on a gluten-containing diet: villous atrophy, crypt hyperplasia and intra-epithelial lymphocytosis.1 Serological tests for coeliac disease, such as for endomysial IgA or transglutaminase IgA, are predictive, but alone are not sufficient for diagnosis. The diagnosis of coeliac disease is confirmed by clinical, serological or histological improvement on a gluten-free diet.1
Publication of your online response is subject to the Medical Journal of Australia's editorial discretion. You will be notified by email within five working days should your response be accepted.