A woman presenting with recurrent purpura fulminans was eventually found to have inflammatory bowel disease. We suggest the inflammatory state resulted in a deficiency of functional protein C.
A 28-year-old woman presented to hospital with a 1-week history of diarrhoea (three soft, non-bloody stools daily), 2 days of vomiting, and a 12-hour history of a purpuric truncal rash.
The full article is accessible to AMA
members and paid subscribers.
Login to MJA or subscribe now.
- 1. Stein RH, Sapadin AN. Purpura fulminans. Int J Dermatol 2003; 42: 130-131.
- 2. Nolan J, Sinclair R. Review of management of purpura fulminans and two case reports. Br J Anaesth 2001; 86: 581-586.
- 3. Ward KM, Celebi JT, Gmyrek R, et al. Acute infectious purpura fulminans associated with asplenism or hyposplenism. J Am Acad Dermatol 2002; 47: 493-496.
- 4. Gurgey A, Aytac S, Kanra G, et al. Outcome in children with purpura fulminans: report on 16 patients. Am J Hematol 2005; 80: 20-25.
- 5. Warner PM, Kagan RJ, Yakuboff KP, et al. Current management of purpura fulminans: a multicenter study. J Burn Care Rehabil 2003; 24: 119-126.
- 6. Childers BJ, Cobanov B. Acute infectious purpura fulminans: a 15-year retrospective review of 28 consecutive cases. Am Surg 2003; 69: 86-90.
- 7. Smith OP, White B. Infectious purpura fulminans: diagnosis and treatment. Br J Haematol 1999; 104: 202-207.
- 8. Kravitz GR, Dries DJ, Peterson ML, et al. Purpura fulminans due to Staphylococcus aureus. Clin Infect Dis 2005; 40: 941-947.
- 9. Kempton CL, Bagby G, Collins JF. Ulcerative colitis presenting as purpura fulminans. Inflamm Bowel Dis 2001; 7: 319-322.
Online responses are no longer available. Please refer to our instructions for authors page for more information.
We would like to thank Dr Chong Ong, who supplied one of the clinical pictures.
None identified.