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Precision medicine: are we there?

Ingrid Winship
Med J Aust 2015; 203 (3): . || doi: 10.5694/mja15.00236
Published online: 3 August 2015

Implementation of precision medicine requires a multidisciplinary and systematic approach

In his State of the Union address on 20 January 2015, United States President Barack Obama announced a new initiative in precision medicine, which aims to give “access to the personalised information we need to keep ourselves and our families healthier”.1 So, what is precision medicine? Previously referred to as personalised medicine, it can be defined as the correlation of innate and external factors at an individual level, to better understand the pattern of disease and its impact on the individual, and thus to tailor prevention, intervention and treatment. Precision medicine thus combines genomic and epigenomic data with environmental exposure and lifestyle factors. It has the potential not only to improve health outcomes but to save money by better targeting health interventions to those individuals most likely to benefit.


  • Melbourne Health, Melbourne, VIC


Correspondence: Ingrid.Winship@mh.org.au

Acknowledgements: 

I am indebted to Terence O’Brien and Melissa Southey who reviewed the manuscript.

Competing interests:

I am a member of the National Health and Medical Research Council Human Genetics Advisory Committee.

  • 1. The White House, Office of the Press Secretary (US). Remarks by the President in State of the Union address. January 20, 2015. https://www.whitehouse.gov/the-press-office/2015/01/20/remarks-president-state-union-address-january-20-2015 (accessed Apr 2015).
  • 2. Collins FS, Varmus H. A new initiative on precision medicine. N Engl J Med 2015; 372: 793-795.
  • 3. Ward RL. A decade of promises in personalised cancer medicine: is the honeymoon over? Med J Aust 2014; 200: 132-133. <MJA full text>
  • 4. Chen Z, Liew D, Kwan P. Real-world efficiency of pharmacogenetic screening for carbamazepine-induced severe cutaneous adverse reactions. PLOS One 2014; 9: e96990.
  • 5. ACMG Board of Directors. ACMG policy statement: updated recommendations regarding analysis and reporting of secondary findings in clinical genome-scale sequencing. Genet Med 2015; 17: 68-69.
  • 6. National Health and Medical Research Council Human Genetics Advisory Committee. Principles for the translation of ‘omics’-based tests from discovery to health care. Council version — 12 June 2014. Canberra: NHMRC, 2014. http://consultations.nhmrc.gov.au/files/consultations/drafts/attaevidentialstandardsdocument.pdf (accessed Apr 2015)

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