What influenza activity can we anticipate in 2022?

Kanta Subbarao
Med J Aust 2022; 216 (5): . || doi: 10.5694/mja2.51437
Published online: 7 March 2022

We were spared influenza co‐circulating with SARS‐CoV‐2 since 2020, but that is likely to change

Influenza seasons in temperate Australia typically begin in June, peak in August and trail off by October, with some variability from year to year, whereas influenza activity occurs in two periods in the tropical north.1 Since the global spread of severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) in early 2020, we have not experienced seasonal influenza in Australia; effectively, we were spared influenza circulating concurrently with SARS‐CoV‐2 in 2020 and 2021. Globally, there was virtually no influenza reported after mid‐March in 2020, but influenza activity was reported in 2021 from a few countries (Box, A, C and D), most notably in western Africa and the Indian subcontinent, and the number of cases was small. Several factors, which occurred variably in different countries and even within countries, contributed to the absence of influenza activity during the coronavirus disease 2019 (COVID‐19) pandemic. These included restrictions on international travel; mandatory quarantine for returned travellers; working from home; school closures; social and public health measures, such as mask wearing, physical distancing and hand hygiene; and, potentially, viral interference.2 These factors are not specific to influenza, as evidenced by the fact that the other major seasonal respiratory virus, respiratory syncytial virus, also did not circulate in its normal autumn–winter pattern in Australia in 2020 but re‐emerged in spring 2020 in some states (New South Wales and Western Australia) and in summer 2021 in others (Victoria and Queensland).3

  • WHO Collaborating Centre for Reference and Research on Influenza, Doherty Institute, Melbourne, VIC


The Melbourne WHO Collaborating Centre for Reference and Research on Influenza is supported by the Australian Government Department of Health.

Competing interests:

No relevant disclosures.

  • 1. Barr IG, Deng YM, Grau ML, et al. Intense interseasonal influenza outbreaks, Australia, 2018/19. Euro Surveill 2019; 24: 1900421.
  • 2. Sullivan SG, Carlson S, Cheng AC, et al. Where has all the influenza gone? The impact of COVID‐19 on the circulation of influenza and other respiratory viruses, Australia, March to September 2020. Euro Surveill 2020; 25: 2001847.
  • 3. Eden JS, Sikazwe C, Xie R, et al. Off‐season RSV epidemics in Australia after easing of COVID‐19 restrictions [preprint]. medRxiv 21260810. 24 July 2021. (viewed Feb 2022).
  • 4. Geoghegan JL, Saavedra AF, Duchene S, et al. Continental synchronicity of human influenza virus epidemics despite climatic variation. PLoS Pathog 2018; 14: e1006780.
  • 5. Sullivan SG. Preparing for out‐of‐season influenza epidemics when international travel resumes. Med J Aust 2021; 216: 25–26.‐out‐season‐influenza‐epidemics‐when‐international‐travel‐resumes
  • 6. van Diemen A. Avian influenza detected in Victorian poultry, 2020.‐advisories/avian‐influenza‐detected‐in‐victorian‐poultry (viewed Feb 2022).
  • 7. Wong FYK, Donato C, Deng YM, et al. Divergent human‐origin influenza viruses detected in Australian swine populations. J Virol 2018; 92: 00316–00318.
  • 8. Deng YM, Wong FYK, Spirason N, et al. Locally acquired human infection with swine‐origin influenza A(H3N2) variant virus, Australia, 2018. Emerg Infect Dis 2020; 26: 143–147.
  • 9. World Health Organization. Antigenic and genetic characteristics of zoonotic influenza A viruses and development of candidate vaccine viruses for pandemic preparedness. Wkly Epidemiol Rec 2021; 96: 521–535.
  • 10. Subbarao K, Klimov A, Katz J, et al. Characterization of an avian influenza A (H5N1) virus isolated from a child with a fatal respiratory illness. Science 1998; 279: 393–396.
  • 11. Holmes EC, Goldstein SA, Rasmussen AL, et al. The origins of SARS‐CoV‐2: a critical review. Cell 2021; 184: 4848–4856.
  • 12. Wang J, Anderson DE, Halpin K, et al. A new Hendra virus genotype found in Australian flying foxes. Virol J 2021; 18: 197.


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