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Chimeric antigen receptor T‐cell therapy for haematological malignancies

Adrian G Selim and Constantine S Tam
Med J Aust || doi: 10.5694/mja2.50783
Published online: 21 September 2020

The advent of CAR T‐cell therapy has seen significant improvements in survival and is a potential cure for patients with advanced haematological malignancies

Cancer immunotherapy is a burgeoning field which, in the last decade, has produced unprecedented improvements in outcomes across a variety of advanced malignancies. The eventual translation of decades of research into clinically available immunotherapies stems from the expanded knowledge of the role that the immune system plays in preventing tumour initiation and progression as well as the mechanisms by which tumours learn to evade this immune surveillance.1

  • Adrian G Selim
  • Constantine S Tam

  • Peter MacCallum Cancer Centre, Melbourne, VIC


Competing interests:

Adrian Selim has received honoraria from Novartis. Constantine Tam was a principal investigator on the JULIET study sponsored by Novartis, and receives research funding from Janssen and AbbVie, and honoraria from Janssen, AbbVie, BeiGene, Novartis and Roche.

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