Difficulties in knowing which critical care trial data warrant change in practice

Benjamin Reddi, Mark Finnis and Sandra Peake
Med J Aust 2019; 211 (7): . || doi: 10.5694/mja2.50331
Published online: 7 October 2019

Why is some strong evidence ignored while some weak evidence is rapidly acted upon?

Most clinicians aspire to practise evidence‐based medicine, no longer believing it acceptable to implement novel interventions simply because they “make sense” or remain untested. However, external influences, psychological factors, and misapplied statistical techniques may hinder rational decision making. Using examples from intensive care literature, we discuss why well supported therapies are not always readily adopted, while poorly supported interventions may be unduly welcomed into practice.

  • Benjamin Reddi1
  • Mark Finnis1
  • Sandra Peake2

  • 1 Royal Adelaide Hospital, Adelaide, SA
  • 2 Queen Elizabeth Hospital, Adelaide, SA


Competing interests:

No relevant disclosures.


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