A 79-year-old woman presented with 10 kg unintentional weight loss, anorexia, fatigue and cough over 3 months on a background of 50 pack-years smoking history. Physical examination revealed digital clubbing and velvety thickened palms with accentuated skin markings consistent with tripe palms (Figure, A and B). A whole-body positron emission tomography/computed tomography scan revealed a 6.4 cm left upper lobe lung mass intensely fludeoxyglucose avid. Subsequent computed tomography scan-guided biopsy revealed KRAS-mutant adenocarcinoma. Tripe palms or acanthosis palmaris is a rare manifestation of internal malignancy, most notably lung or gastric cancer.1 The patient declined further treatment and opted for palliative care.
The full article is accessible to AMA
members and paid subscribers.
Login to MJA or subscribe now.
- 1. Breathnach SM, Wells GC. Acanthosis palmaris: tripe palms. A distinctive pattern of palmar keratoderma frequently associated with internal malignancy. Clin Exp Dermatol 1980; 5: 181-189.
Online responses are no longer available. Please refer to our instructions for authors page for more information.
No relevant disclosures.