Pancreatic cancer is likely to become one of the leading causes of cancer death in Australia
Pancreatic cancer is the 10th most frequently occurring cancer but the fifth most common cause of cancer death in Australia, as is also seen in other developed regions of the world.1 A gradual increase in incidence has been observed since the 1980s in almost all age groups in both sexes in Australia (Box 1).3 Increases have been attributed only to trends in smoking, which is considered causal,4 with local published data suggesting a lag of about 30 years between smoking trends and incidence.5 However, overweight and obesity may also have contributed, in part, to incidence trends.6
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- 12. Burmeister EA, O'Connell DL, Beesley VL, et al. Describing patterns of care in pancreatic cancer - a population-based study. Pancreas 2015. In press.
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- 14. Bilimoria KY, Bentrem DJ, Ko CY, et al. National failure to operate on early stage pancreatic cancer. Ann Surg 2007; 246: 173-180.
- 15. Chang DK, Merrett ND, Biankin AV. Improving outcomes for operable pancreatic cancer: is access to safer surgery the problem? J Gastroenterol Hepatol 2008; 23: 1036-1045.
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- 17. Waddell N, Pajic M, Patch AM, et al. Whole genomes redefine the mutational landscape of pancreatic cancer. Nature 2015; 518: 495-501.
- 18. Le DT, Wang-Gillam A, Picozzi V, et al. Safety and survival with GVAX pancreas prime and Listeria monocytogenes-expressing mesothelin (CRS-207) boost vaccines for metastatic pancreatic cancer. J Clin Oncol 2015; Jan 12. pii: JCO.2014.57.4244. [Epub ahead of print].
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