Skin rash, a kidney mass and a family mystery dating back to World War II

Christopher W Toon, Csilla Hasovits, Julie Paik, Michael Field, Angela Chou, Thomas J Hugh, Nicholas Pavlakis and Anthony J Gill
Med J Aust 2014; 201 (1): 58-60. || doi: 10.5694/mja13.00230

This case of hereditary leiomyomatosis and renal cell cancer in a young man illustrates the importance of considering a hereditary basis for renal cancer in a young patient, and highlights how targeted therapy underpins modern personalised medicine in renal oncology.

A 25-year-old white man presented with a year-long history of malaise, a palpable right loin mass and a painless nodular rash over his back of indeterminate duration. Computed tomography (CT) showed a right renal mass with para-aortic and retroperitoneal lymphadenopathy. The patient underwent radical nephrectomy and para-aortic lymphadenectomy.

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  • Christopher W Toon1
  • Csilla Hasovits1
  • Julie Paik2
  • Michael Field3
  • Angela Chou2
  • Thomas J Hugh3
  • Nicholas Pavlakis3
  • Anthony J Gill3

  • 1 Kolling Institute of Medical Research, Sydney, NSW.
  • 2 St Vincent's Hospital, Sydney, NSW.
  • 3 Royal North Shore Hospital, Sydney, NSW.


Competing interests:

No relevant disclosures.

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