Severe symptomatic hypocalcaemia following a single dose of denosumab

Jennifer M McLachlan, Gavin M Marx and Margaret Bridgman
Med J Aust 2013; 199 (4): . || doi: 10.5694/mja13.10038
Published online: 2 September 2013

To the Editor: Denosumab, a receptor activator of nuclear factor κ-B (RANK) ligand inhibitor, is now considered first-line therapy to prevent skeletal-related events in patients with bone metastases secondary to breast cancer and castration-resistant prostate cancer.1,2

  • Jennifer M McLachlan
  • Gavin M Marx
  • Margaret Bridgman

  • Sydney Adventist Hospital, Sydney, NSW.



We thank the patient for allowing us to report this case.

Competing interests:

No relevant disclosures.


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