Overactive bladder in men as a marker of cardiometabolic risk

Gary A Wittert, Sean Martin, Peter Sutherland, Susan Hall, Varant Kupelian and Andre Araujo
Med J Aust 2012; 197 (7): . || doi: 10.5694/mja11.11318
Published online: 1 October 2012

Overactive bladder may be a marker of obstructive sleep apnoea or cardiometabolic risk

The lower urinary tract symptoms (LUTS) nocturia, urgency and frequency are grouped as “storage symptoms”. When troublesome, the presence of urgency plus one other symptom constitute overactive bladder (OAB).1 Dysfunction or irritability of the detrusor muscle of the urinary bladder is a primary cause of these symptoms, although coexistent prostatic disorders may be contributory. Based on American Urological Association symptom index scores, OAB affects about 25% of Australian men over the age of 40 years, and almost 50% of Australian men over the age of 70.2 It is associated with significant distress and very high direct and indirect costs.3

  • Gary A Wittert1,2
  • Sean Martin1
  • Peter Sutherland2
  • Susan Hall3
  • Varant Kupelian3
  • Andre Araujo3

  • 1 University of Adelaide, Adelaide, SA.
  • 2 Royal Adelaide Hospital, Adelaide, SA.
  • 3 Epidemiology, New England Research Institutes, Watertown, Mass, USA.


This work was supported by the National Health and Medical Research Council (Project Grant No. 627227).

Competing interests:

Peter Sutherland is a member of the Lilly and Pfizer advisory boards and has received research funding and speaking fees from both. Gary Wittert is the Independent Chair of the Weight Management Council Australia and receives research support from Weight Watchers.


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